Detalhe da pesquisa
1.
Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2.
Nucleic Acids Res
; 42(12): 7748-61, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24880691
2.
The Werner syndrome protein promotes CAG/CTG repeat stability by resolving large (CAG)(n)/(CTG)(n) hairpins.
J Biol Chem
; 287(36): 30151-6, 2012 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22787159
3.
Molecular cooperation between the Werner syndrome protein and replication protein A in relation to replication fork blockage.
J Biol Chem
; 286(5): 3497-508, 2011 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21107010
4.
The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks.
Biochemistry
; 50(32): 6774-88, 2011 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21736299
5.
Replication fork regression in vitro by the Werner syndrome protein (WRN): holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity.
Nucleic Acids Res
; 35(17): 5729-47, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17717003
6.
Lysine Acetylation of Proteins and Its Characterization in Human Systems.
Methods Mol Biol
; 1983: 107-130, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31087295
7.
Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domains.
BMC Mol Biol
; 7: 6, 2006 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16503984
8.
Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
BMC Mol Biol
; 7: 1, 2006 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-16412221
9.
TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA.
Oncogene
; 23(1): 149-56, 2004 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-14712220
10.
The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events.
Nat Commun
; 6: 8331, 2015 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26420422
11.
Intramolecular telomeric G-quadruplexes dramatically inhibit DNA synthesis by replicative and translesion polymerases, revealing their potential to lead to genetic change.
PLoS One
; 9(1): e80664, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24454683
12.
The Werner and Bloom syndrome proteins catalyze regression of a model replication fork.
Biochemistry
; 45(47): 13939-46, 2006 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17115688
13.
RecQ family members combine strand pairing and unwinding activities to catalyze strand exchange.
J Biol Chem
; 280(24): 23397-407, 2005 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-15845538
14.
DNase I footprinting and enhanced exonuclease function of the bipartite Werner syndrome protein (WRN) bound to partially melted duplex DNA.
J Biol Chem
; 277(6): 4492-504, 2002 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-11717307
15.
The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro.
Biochemistry
; 41(46): 13483-8, 2002 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-12427008
16.
Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2.
Hum Mol Genet
; 13(17): 1919-32, 2004 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15229185