RESUMO
BACKGROUND: In the last years, numerous studies evaluated different tools for the diagnosis of positional plagiocephaly (PP). The purpose of this study was to evaluate ultrasonography (US) as a first line screening test of lambdoid sutural patency in child with PP and to compare our results with the literature. METHODS: All consecutive patients who referred to our Institute from January 2016 to October 2017 with the suspicion of PP, were included in the study and performed US examination of the lambdoid sutures. A 3-6-month clinical follow-up was performed by a pediatric neurosurgeon or a pediatrician to confirm the diagnosis of PP. RESULTS: Thirty-five children performed US examination and in all cases the diagnosis of PP was confirmed. No cases of anticipated suture fusion were examined during this period. The concordance between US findings and clinical exam follow-up was 100%. CONCLUSIONS: Ultrasonography of the lambdoid sutures represents an ideal first-line screening test and reliable alternative to other diagnostic techniques for lambdoid sutural patency in child with PP, being radiation free, fast and cheap.
Assuntos
Craniossinostoses , Plagiocefalia não Sinostótica , Humanos , Criança , Plagiocefalia não Sinostótica/diagnóstico por imagem , Craniossinostoses/diagnóstico , Craniossinostoses/cirurgia , Suturas Cranianas/diagnóstico por imagem , Ultrassonografia , Tomografia Computadorizada por Raios X/métodosRESUMO
An HHV-8-related visceral KS was diagnosed in a 10-yr-old boy after partially matched allogeneic HSCT. This complication occurred 463 days after HSCT and involved tonsils, lymph nodes, hard palate, lung, skin, and paranasal sinuses. Treatment with pegylated liposomal doxorubicin induced long-term remission (33 months) of this disease. HHV-8 infection is quite frequent after HSCT, but KS, and especially its visceral form, is a very rare complication, and its association with HHV-8 has been documented even less frequently. However, our observation suggests that HHV-8-related KS should be taken into consideration in the differential diagnosis of late post-HSCT complications.
Assuntos
Transplante de Células-Tronco Hematopoéticas/efeitos adversos , Herpesvirus Humano 8/metabolismo , Leucemia Mieloide Aguda/terapia , Sarcoma de Kaposi/complicações , Sarcoma de Kaposi/virologia , Criança , Diagnóstico Diferencial , Progressão da Doença , Doxorrubicina/análogos & derivados , Doxorrubicina/farmacologia , Humanos , Leucemia Mieloide Aguda/complicações , Masculino , Polietilenoglicóis/farmacologia , Tomografia por Emissão de Pósitrons/métodos , Indução de Remissão , Tomografia Computadorizada por Raios X/métodosRESUMO
Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system and malignant rhabdoid tumor of the kidney (MRTK) may present with different responses to chemotherapy and outcomes. We describe the case of an infant with multifocal rhabdoid tumor with different behavior and response to treatment, depending on the anatomic site.