Detalhe da pesquisa
1.
Siponimod: Disentangling disability and relapses in secondary progressive multiple sclerosis.
Mult Scler
; 27(10): 1564-1576, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205682
2.
Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria.
N Engl J Med
; 375(12): 1152-60, 2016 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27653565
3.
Bayesian inference for a principal stratum estimand to assess the treatment effect in a subgroup characterized by postrandomization event occurrence.
Stat Med
; 38(23): 4761-4771, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31386219
4.
Phase II Study of Single/Repeated Doses of Acumapimod (BCT197) to Treat Acute Exacerbations of COPD.
COPD
; 16(5-6): 344-353, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31682162
5.
How can we make better graphs? An initiative to increase the graphical expertise and productivity of quantitative scientists.
Pharm Stat
; 18(1): 106-114, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30378733
6.
Estimation of the In Vivo MIC of Cipargamin in Uncomplicated Plasmodium falciparum Malaria.
Antimicrob Agents Chemother
; 61(2)2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27872070
7.
Spiroindolone KAE609 for falciparum and vivax malaria.
N Engl J Med
; 371(5): 403-10, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25075833
8.
Model averaging for treatment effect estimation in subgroups.
Pharm Stat
; 16(2): 133-142, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27935199
9.
A First-in-Human Study To Assess the Safety and Pharmacokinetics of Monoclonal Antibodies against Human Cytomegalovirus in Healthy Volunteers.
Antimicrob Agents Chemother
; 60(5): 2881-7, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26926639
10.
The oral CRTh2 antagonist QAW039 (fevipiprant): A phase II study in uncontrolled allergic asthma.
Pulm Pharmacol Ther
; 39: 54-63, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27354118
11.
A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel antimalarial Spiroindolone KAE609 (Cipargamin) to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers.
Antimicrob Agents Chemother
; 58(10): 6209-14, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25114127
12.
A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel Imidazolopiperazine KAF156 to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers.
Antimicrob Agents Chemother
; 58(11): 6437-43, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25136017
13.
Group sequential enrichment design incorporating subgroup selection.
Stat Med
; 32(16): 2695-714, 2013 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23315698
14.
A framework to guide dose & regimen strategy for clinical drug development.
CPT Pharmacometrics Syst Pharmacol
; 10(11): 1276-1280, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34562310
15.
White matter lesion location correlates with disability in relapsing multiple sclerosis.
Mult Scler J Exp Transl Clin
; 6(1): 2055217320906844, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32128236
16.
Effective Visual Communication for the Quantitative Scientist.
CPT Pharmacometrics Syst Pharmacol
; 8(10): 705-719, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31329354
17.
How Often Do Safety Signals Occur by Chance in First-in-Human Trials?
Clin Transl Sci
; 11(5): 471-476, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29702733
18.
The Safety and Antiviral Activity of BZF961 with or without Ritonavir in Patients Infected with Hepatitis C Virus: A Randomized, Multicenter Trial.
Clin Ther
; 40(9): 1567-1581.e4, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185394
19.
Data on the oral CRTh2 antagonist QAW039 (fevipiprant) in patients with uncontrolled allergic asthma.
Data Brief
; 9: 199-205, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27656673