Detalhe da pesquisa
1.
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis.
Neuropathol Appl Neurobiol
; 49(1): e12851, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36181265
2.
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis.
Acta Neuropathol
; 141(2): 257-279, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398403
3.
Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis.
J Neurol Neurosurg Psychiatry
; 92(3): 295-302, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184094
4.
Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis.
Acta Neuropathol
; 140(2): 143-167, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32572598
5.
Deletion of the Mitochondrial Complex-IV Cofactor Heme A:Farnesyltransferase Causes Focal Segmental Glomerulosclerosis and Interferon Response.
Am J Pathol
; 188(12): 2745-2762, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30268775
6.
Respiration-Deficient Astrocytes Survive As Glycolytic Cells In Vivo.
J Neurosci
; 37(16): 4231-4242, 2017 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28314814
7.
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity.
Nature
; 485(7399): 517-21, 2012 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22622581
8.
Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short-term facilitation at mossy fibre to CA3 pyramidal cell synapses.
J Physiol
; 595(6): 2147-2160, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28083896
9.
Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons.
Proc Natl Acad Sci U S A
; 111(27): 9953-8, 2014 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24958879
10.
Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier.
J Neurosci
; 35(5): 2246-54, 2015 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25653379
11.
Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.
Acta Neuropathol
; 131(2): 281-298, 2016 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26687980
12.
Temporal lobe cortical pathology and inhibitory GABA interneuron cell loss are associated with seizures in multiple sclerosis.
Mult Scler
; 22(1): 25-35, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25921040
13.
Mitochondrial fission augments capsaicin-induced axonal degeneration.
Acta Neuropathol
; 129(1): 81-96, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25322817
14.
Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.
Acta Neuropathol
; 128(2): 247-66, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24622774
15.
The central role of mitochondria in axonal degeneration in multiple sclerosis.
Mult Scler
; 20(14): 1806-13, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122475
16.
Disease-specific molecular events in cortical multiple sclerosis lesions.
Brain
; 136(Pt 6): 1799-815, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23687122
17.
No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis.
Mult Scler
; 19(14): 1858-66, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23787892
18.
NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury.
Brain
; 135(Pt 3): 886-99, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22366799
19.
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions.
Nat Metab
; 5(8): 1364-1381, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37430025
20.
Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons.
bioRxiv
; 2023 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214873