Detalhe da pesquisa
1.
Substrate-targeting gamma-secretase modulators.
Nature
; 453(7197): 925-9, 2008 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18548070
2.
Synthesis of a DOTA (Gd3+)-conjugate of proton-pump inhibitor pantoprazole for gastric wall imaging studies.
Bioorg Med Chem Lett
; 23(9): 2808-11, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23511016
3.
A convenient synthesis of (Z)-4-hydroxy-N-desmethyltamoxifen (endoxifen).
Bioorg Med Chem Lett
; 20(10): 3036-8, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20400308
4.
Chemical synthesis of deuterium-labeled and unlabeled very long chain polyunsaturated fatty acids.
Tetrahedron Lett
; 51(49): 6426-6428, 2010 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21076635
5.
Hydrolysis of low concentrations of the acetylthiocholine analogs acetyl(homo)thiocholine and acetyl(nor)thiocholine by acetylcholinesterase may be limited by selective gating at the enzyme peripheral site.
Chem Biol Interact
; 203(1): 38-43, 2013 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23047027
6.
Binding of antitumor tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen to human serum albumin.
Biochimie
; 93(7): 1089-101, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21439346
7.
Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin.
Eur J Med Chem
; 46(9): 4344-53, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21777996
8.
Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.
PLoS One
; 5(5): e10504, 2010 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20498699
9.
Rationally designed dehydroalanine (DeltaAla)-containing peptides inhibit amyloid-beta (Abeta) peptide aggregation.
Biopolymers
; 91(6): 456-65, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19189374
10.
Mild and efficient synthesis of new tetraketones as lipoxygenase inhibitors and antioxidants.
J Enzyme Inhib Med Chem
; 23(1): 62-9, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18341255
11.
A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers.
Bioorg Med Chem Lett
; 17(22): 6392-5, 2007 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17897827
12.
A facile and improved synthesis of sildenafil (Viagra) analogs through solid support microwave irradiation possessing tyrosinase inhibitory potential, their conformational analysis and molecular dynamics simulation studies.
Mol Divers
; 9(1-3): 15-26, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15789547
13.
Synthesis and inhibitory potential towards acetylcholinesterase, butyrylcholinesterase and lipoxygenase of some variably substituted chalcones.
J Enzyme Inhib Med Chem
; 20(1): 41-7, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15895683
14.
Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors.
J Enzyme Inhib Med Chem
; 20(4): 401-7, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16206837
15.
Antibacterial and antifugal mono- and di-substituted symmetrical and unsymmetrical triazine-derived Schiff-bases and their transition metal complexes.
J Enzyme Inhib Med Chem
; 19(2): 161-8, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15449731
16.
Antifungal cobalt(II), copper(II), nickel(II) and zinc(II) complexes of furanyl-,thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins.
J Enzyme Inhib Med Chem
; 19(1): 85-90, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15202498
17.
Synthesis and urease enzyme inhibitory effects of some dicoumarols.
J Enzyme Inhib Med Chem
; 19(4): 367-71, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15558955