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1.
Appl Radiat Isot ; 155: 108901, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31655354

RESUMO

Silicone being a hybrid elastomer is well known for its excellent thermal and mechanical properties, chemical resistance, compatibility with organic and inorganic fillers, nontoxicity, and flexibility. As the reported literature on silicone tungsten composite is rare, thus, a complete possible spectrum of silicone tungsten composites series with tungsten loading of 0-88.1 %wt has been fabricated by RTV method and studied as a flexible gamma shielding material. Flexible silicone/tungsten composite formulations containing different weight percentages of tungsten powder (0, 30.1, 47.8, 59.8, 68.1, and 88.1 wt %) were developed by the room-temperature vulcanization route. Two lead collimators with diameters of 0.6 cm were used to make a narrow beam geometry for gamma rays emitted from a137Cs (gamma-ray energy of 662 keV) point source. Uncollided flux was measured with a NaI(Tl) scintillation detector enclosed in lead shielding to reduce the background radiation level. The measured mass attenuation coefficient for our composites with 88.1 wt % tungsten was 0.1035 cm2/g, which is nearly 3.5% higher than that of commercially available silicone/tungsten composites named T-Flex (nearly 0.095 cm2/g) containing the same tungsten loading. Similarly, superior half value layers (HVL) of our composites with 88.1 % wt loading of tungsten i.e 1.01 cm versus 1.27 cm for the reported T-Flex counterpart with additional advantage of insitu fabrication on complex geometries. It was also found that the effectiveness of gamma-ray shielding increases with increase in density of the composites, which is due to the increase in the weight percent of tungsten powder. Our material will have applications as shielding material for both mobile and stationary radiation sources and it can also be used as fabrication material for gloves, safety shoes, coats, etc. to protect workers in a radiation environment.

2.
Artigo em Inglês | MEDLINE | ID: mdl-24110223

RESUMO

In order to obtain plasma time activity curve (PTAC), input function for almost all quantitative PET studies, patient blood is sampled manually from the artery or vein which has various drawbacks. Recently a novel compact Time over Threshold (ToT) based Pr:LuAG-APD animal PET tomograph is developed in our laboratory which has 10% energy resolution, 4.2 ns time resolution and 1.76 mm spatial resolution. The measured value of spatial resolution shows much promise for imaging the blood vascular, i.e; artery of diameter 2.3-2.4mm, and hence, to measure PTAC for quantitative PET studies. To find the measurement time required to obtain reasonable counts for image reconstruction, the most important parameter is the sensitivity of the system. Usually small animal PET systems are characterized by using a point source in air. We used Electron Gamma Shower 5 (EGS5) code to simulate a point source at different positions inside the sensitive volume of tomograph and the axial and radial variations in the sensitivity are studied in air and phantom equivalent water cylinder. An average sensitivity difference of 34% in axial direction and 24.6% in radial direction is observed when point source is displaced inside water cylinder instead of air.


Assuntos
Tomografia por Emissão de Pósitrons/instrumentação , Compostos Radiofarmacêuticos/sangue , Alumínio/química , Animais , Humanos , Lutécio/química , Óxidos/química , Imagens de Fantasmas , Tomografia por Emissão de Pósitrons/métodos , Praseodímio/química , Sensibilidade e Especificidade
3.
Artigo em Inglês | MEDLINE | ID: mdl-24110894

RESUMO

Ce(+3): Gd3Al2Ga3O12 (Ce:GAGG) is expected to be promising scintillator for PET, SPECT, and gamma camera applications because of its attractive properties. We designed a Compton camera based on Ce:GAGG, both as scatterer and absorber, for imaging and radioactivity measurement of point sources. The two important parameters sensitivity and spatial resolution are determined for 4 × 4 pixels, each pixel of size 1 × 1 cm(2), for both scatterer and absorber. Our main focus in this paper is to image a distant source for which sensitivity is of prime importance. High sensitivity and light weight are two important advantages of Compton camera for distant source imaging and the availability of Ce:GAGG 3 × 3 mm(2) pixel size is expected to give a spatial resolution of ~ 5 mm for medical applications as well.


Assuntos
Diagnóstico por Imagem/métodos , Câmaras gama , Tomografia Computadorizada de Emissão de Fóton Único/métodos , Algoritmos , Simulação por Computador , Desenho de Equipamento , Humanos , Reprodutibilidade dos Testes , Espalhamento de Radiação
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