Detalhe da pesquisa
1.
Multiple functional neurosteroid binding sites on GABAA receptors.
PLoS Biol
; 17(3): e3000157, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30845142
2.
Development of New CD38 Targeted Peptides for Cancer Imaging.
Mol Imaging Biol
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38480650
3.
Induction of complementary immunogenic necroptosis and apoptosis cell death pathways inhibits cancer metastasis and relapse.
Res Sq
; 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38558990
4.
Transferrin receptor in primary and metastatic breast cancer: Evaluation of expression and experimental modulation to improve molecular targeting.
PLoS One
; 18(12): e0293700, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117806
5.
Neurosteroid analog photolabeling of a site in the third transmembrane domain of the ß3 subunit of the GABA(A) receptor.
Mol Pharmacol
; 82(3): 408-19, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22648971
6.
Analysis of Stable Chelate-free Gadolinium Loaded Titanium Dioxide Nanoparticles for MRI-Guided Radionuclide Stimulated Cancer Treatment.
Curr Anal Chem
; 18(7): 826-835, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-36561765
7.
Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light.
Nat Neurosci
; 10(4): 523-30, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17322875
8.
A synthetic 18-norsteroid distinguishes between two neuroactive steroid binding sites on GABAA receptors.
J Pharmacol Exp Ther
; 333(2): 404-13, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20124410
9.
Neurosteroid analogues. 15. A comparative study of the anesthetic and GABAergic actions of alphaxalone, Δ16-alphaxalone and their corresponding 17-carbonitrile analogues.
Bioorg Med Chem Lett
; 20(22): 6680-4, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20875742
10.
Photodynamic effects of steroid-conjugated fluorophores on GABAA receptors.
Mol Pharmacol
; 76(4): 754-65, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19596835
11.
Neurosteroid analogues. 14. Alternative ring system scaffolds: GABA modulatory and anesthetic actions of cyclopenta[b]phenanthrenes and cyclopenta[b]anthracenes.
J Med Chem
; 51(5): 1309-18, 2008 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18275132
12.
Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens.
Eur J Med Chem
; 43(1): 107-13, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17434649
13.
Neurosteroid analogues. 11. Alternative ring system scaffolds: gamma-aminobutyric acid receptor modulation and anesthetic actions of benz[f]indenes.
J Med Chem
; 49(15): 4595-605, 2006 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16854065
14.
Activation and modulation of recombinant glycine and GABAA receptors by 4-halogenated analogues of propofol.
Br J Pharmacol
; 173(21): 3110-3120, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27459129
15.
Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
J Med Chem
; 48(8): 3051-9, 2005 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15828844
16.
Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
J Med Chem
; 46(25): 5334-48, 2003 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-14640542
17.
Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.
J Med Chem
; 57(1): 171-90, 2014 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24328079
18.
11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors.
Psychopharmacology (Berl)
; 231(17): 3479-91, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24756762
19.
Neurosteroid analogues. 17. Inverted binding orientations of androsterone enantiomers at the steroid potentiation site on γ-aminobutyric acid type A receptors.
J Med Chem
; 55(3): 1334-45, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22191644
20.
Characteristics of concatemeric GABA(A) receptors containing α4/δ subunits expressed in Xenopus oocytes.
Br J Pharmacol
; 165(7): 2228-43, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21950777