Detalhe da pesquisa
1.
Actein contributes to black cohosh extract-induced genotoxicity in human TK6 cells.
J Appl Toxicol
; 42(9): 1491-1502, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35261072
2.
Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans.
J Pineal Res
; 70(3): e12726, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33638890
3.
Performance of high-throughput CometChip assay using primary human hepatocytes: a comparison of DNA damage responses with in vitro human hepatoma cell lines.
Arch Toxicol
; 94(6): 2207-2224, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32318794
4.
Silicon Dioxide Impedes Antiviral Response and Causes Genotoxic Insult During Calicivirus Replication.
J Nanosci Nanotechnol
; 16(7): 7720-7730, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27547159
5.
Evaluation of weak genotoxicity of hydroxychloroquine in human TK6 cells.
Toxicol Lett
; 393: 84-95, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38311193
6.
In vivo genotoxicity of furan in F344 rats at cancer bioassay doses.
Toxicol Appl Pharmacol
; 261(2): 164-71, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22507866
7.
Expression analysis of hepatic mitochondria-related genes in mice exposed to acrylamide and glycidamide.
J Toxicol Environ Health A
; 75(6): 324-39, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22480170
8.
Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug-related metabolite, or drug-related impurity.
Mutat Res Genet Toxicol Environ Mutagen
; 868-869: 503386, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34454692
9.
Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells.
Toxicol Sci
; 182(1): 96-106, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33856461
10.
Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines.
Food Chem Toxicol
; 145: 111662, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32798647
11.
Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing.
Toxicol Sci
; 175(2): 251-265, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32159784
12.
Evaluation of Macaca mulatta as a model for genotoxicity studies.
Mutat Res
; 673(1): 21-8, 2009 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19073277
13.
Evaluation of mutagenic mode of action in Big Blue mice fed methylphenidate for 24 weeks.
Mutat Res
; 680(1-2): 43-8, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19778631
14.
The genetic toxicology of methylphenidate hydrochloride in non-human primates.
Mutat Res
; 673(1): 59-66, 2009 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19135169
15.
The development and validation of EpiComet-Chip, a modified high-throughput comet assay for the assessment of DNA methylation status.
Environ Mol Mutagen
; 58(7): 508-521, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28755435
16.
Dose and temporal evaluation of ethylene oxide-induced mutagenicity in the lungs of male big blue mice following inhalation exposure to carcinogenic concentrations.
Environ Mol Mutagen
; 58(3): 122-134, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28326610
17.
Genotoxicity of acrylamide and its metabolite glycidamide administered in drinking water to male and female Big Blue mice.
Environ Mol Mutagen
; 47(1): 6-17, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15957192
18.
Evaluation of cII gene mutation in the brains of Big Blue mice exposed to acrylamide and glycidamide in drinking water.
J Toxicol Sci
; 41(6): 719-730, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27853100
19.
In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver.
J Vis Exp
; (111)2016 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27166647
20.
Titanium Dioxide Nanoparticles Evoke Proinflammatory Response during Murine Norovirus Infection Despite Having Minimal Effects on Virus Replication.
Int J Nanotechnol Eng Med
; 1(3): 63-73, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29930994