Detalhe da pesquisa
1.
Probing the Protein-Excipient Interaction in the Orally Delivered Protein by Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry and Molecular Dynamics.
Anal Chem
; 96(2): 802-809, 2024 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38155586
2.
Predicting Long-Term Stability of an Oral Delivered Antibody Drug Product with Accelerated Stability Assessment Program Modeling.
Mol Pharm
; 21(1): 325-332, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38060811
3.
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.
Bioorg Med Chem Lett
; 27(18): 4370-4376, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28830649
4.
Cyclodextrin Reduces Intravenous Toxicity of a Model Compound.
J Pharm Sci
; 108(6): 1934-1943, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639736
5.
Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.
J Med Chem
; 56(11): 4521-36, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23668484
6.
Lead identification of novel and selective TYK2 inhibitors.
Eur J Med Chem
; 67: 175-87, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23867602