Detalhe da pesquisa
1.
A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
Proc Natl Acad Sci U S A
; 117(40): 24802-24812, 2020 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32958664
2.
Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol Cell
; 53(2): 221-34, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24462203
3.
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.
Mol Cell
; 45(3): 384-97, 2012 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22325355
4.
Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation.
Mol Cell Proteomics
; 16(6): 1111-1125, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28373297
5.
MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
Mol Cell Proteomics
; 16(6): 1098-1110, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28373298
6.
"Unraveling the tail" of how SRPK1 phosphorylates ASF/SF2.
Mol Cell
; 29(5): 535-7, 2008 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18342599
7.
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mol Cell
; 32(2): 259-75, 2008 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-18951093
8.
Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization.
Nat Chem Biol
; 9(7): 428-36, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23685672
9.
Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.
Nucleic Acids Res
; 41(12): 6332-46, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23620299
10.
Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function.
J Biol Chem
; 288(13): 9363-72, 2013 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23389034
11.
Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci
; 33(1): e4824, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37945533
12.
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
J Med Chem
; 65(15): 10251-10284, 2022 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35880755
13.
A substrate binding model for the KEOPS tRNA modifying complex.
Nat Commun
; 11(1): 6233, 2020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33277478
14.
CUL7 is a novel antiapoptotic oncogene.
Cancer Res
; 67(20): 9616-22, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17942889
15.
p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest.
Mol Cell Biol
; 25(17): 7423-31, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16107691
16.
Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.
Structure
; 26(8): 1101-1115.e6, 2018 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29983373
17.
Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression.
Curr Biol
; 13(10): 882-6, 2003 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-12747840
18.
A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
J Mol Biol
; 351(1): 182-94, 2005 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15992821
19.
Promoter-binding and repression of PDGFRB by c-Myc are separable activities.
Nucleic Acids Res
; 32(11): 3462-8, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15226411
20.
c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism.
Oncogene
; 23(19): 3481-6, 2004 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15021909