Detalhe da pesquisa
1.
Anatomic position determines oncogenic specificity in melanoma.
Nature
; 604(7905): 354-361, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355015
2.
Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation.
PLoS Pathog
; 17(6): e1009635, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34143834
3.
Phosphopeptide binding to the N-SH2 domain of tyrosine phosphatase SHP2 correlates with the unzipping of its central ß-sheet.
Comput Struct Biotechnol J
; 23: 1169-1180, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38510972
4.
Methods for Structure Determination of SH2 Domain-Phosphopeptide Complexes by NMR.
Methods Mol Biol
; 2705: 3-23, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37668966
5.
NMR Methods to Study the Dynamics of SH2 Domain-Phosphopeptide Complexes.
Methods Mol Biol
; 2705: 25-37, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37668967
6.
Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains.
Chem Sci
; 14(21): 5743-5755, 2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37265738
7.
Molecular Characterization of Acquired Resistance to KRASG12C-EGFR Inhibition in Colorectal Cancer.
Cancer Discov
; 13(1): 41-55, 2023 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36355783
8.
Phosphotyrosine couples peptide binding and SHP2 activation via a dynamic allosteric network.
Comput Struct Biotechnol J
; 19: 2398-2415, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34025932
9.
Specificity and regulation of phosphotyrosine signaling through SH2 domains.
J Struct Biol X
; 4: 100026, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647828
10.
1H, 13C, 15N chemical shift assignments of SHP2 SH2 domains in complex with PD-1 immune-tyrosine motifs.
Biomol NMR Assign
; 14(2): 179-188, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32236803
11.
Resistance is futile with fourth-generation EGFR inhibitors.
Nat Cancer
; 3(4): 381-383, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35422504