Detalhe da pesquisa
1.
Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity.
Bioorg Chem
; 140: 106794, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37659146
2.
Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands.
Molecules
; 28(8)2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37110664
3.
New Insights into the Opioid Analgesic Profile of cis-(-)-N-Normetazocine-derived Ligands.
Molecules
; 28(12)2023 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37375382
4.
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands.
Bioorg Med Chem Lett
; 72: 128860, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35724925
5.
Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects.
Bioorg Med Chem
; 73: 117032, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36202063
6.
Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain.
Int J Mol Sci
; 23(11)2022 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35682543
7.
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain.
Molecules
; 27(16)2022 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36014375
8.
Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia.
Molecules
; 27(10)2022 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35630697
9.
New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells.
Int J Mol Sci
; 21(6)2020 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32168943
10.
Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands.
Molecules
; 25(8)2020 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32316541
11.
Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products.
Mar Drugs
; 17(2)2019 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30759842
12.
Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands.
Int J Mol Sci
; 20(3)2019 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30678129
13.
A Structure- and Ligand-Based Virtual Screening of a Database of "Small" Marine Natural Products for the Identification of "Blue" Sigma-2 Receptor Ligands.
Mar Drugs
; 16(10)2018 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322188
14.
A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach.
Molecules
; 23(12)2018 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30572684
15.
Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists.
Molecules
; 23(3)2018 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29547588
16.
Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation.
Molecules
; 23(5)2018 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29783634
17.
Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries.
Clin Sci (Lond)
; 131(14): 1701-1712, 2017 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28667068
18.
New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation.
Bioorg Med Chem
; 24(14): 3149-56, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27262426
19.
The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation.
Inflamm Res
; 63(3): 231-7, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316864
20.
Designing drugs optimized for both blood-brain barrier permeation and intra-cerebral partition.
Expert Opin Drug Discov
; 19(3): 317-329, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38145409