Detalhe da pesquisa
1.
Critical Assessment of Artificial Intelligence Methods for Prediction of hERG Channel Inhibition in the "Big Data" Era.
J Chem Inf Model
; 60(12): 6007-6019, 2020 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259212
2.
Argonaute2 expression is post-transcriptionally coupled to microRNA abundance.
RNA
; 19(5): 605-12, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23485552
3.
The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly.
RNA
; 19(11): 1583-93, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24049110
4.
Cell-based assays to support the profiling of small molecules with histone methyltransferase and demethylase modulatory activity.
Drug Discov Today Technol
; 18: 9-17, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26723887
5.
RALDH1 Inhibition Shows Immunotherapeutic Efficacy in Hepatocellular Carcinoma.
Cancer Immunol Res
; 12(2): 180-194, 2024 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38051215
6.
A stele-enriched gene regulatory network in the Arabidopsis root.
Mol Syst Biol
; 7: 459, 2011 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21245844
7.
The interplay between transcription factors and microRNAs in genome-scale regulatory networks.
Bioessays
; 31(4): 435-45, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19274664
8.
High-Throughput Detection of Ligand-Protein Binding Using a SplitLuc Cellular Thermal Shift Assay.
Methods Mol Biol
; 2365: 21-41, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34432237
9.
A Genome-Edited ERα-HiBiT Fusion Reporter Cell Line for the Identification of ERα Modulators Via High-Throughput Screening and CETSA.
Assay Drug Dev Technol
; 19(8): 539-549, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34662221
10.
Genome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for PMP22 Gene-Dosage Disorder Drug Discovery.
ACS Pharmacol Transl Sci
; 4(4): 1422-1436, 2021 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34423274
11.
Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer.
J Med Chem
; 64(8): 4913-4946, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33822623
12.
A Comparative Study of Target Engagement Assays for HDAC1 Inhibitor Profiling.
SLAS Discov
; 25(3): 253-264, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31662025
13.
A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.
Sci Rep
; 10(1): 4203, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144367
14.
Identification of a G-Protein-Independent Activator of GIRK Channels.
Cell Rep
; 31(11): 107770, 2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32553165
15.
Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models.
Sci Adv
; 6(6): eaaz2736, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32128386
16.
Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.
PLoS One
; 13(5): e0197292, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29763427
17.
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
Oncotarget
; 9(4): 4758-4772, 2018 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29435139
18.
A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase.
Sci Rep
; 8(1): 9472, 2018 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29930256
19.
Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.
J Med Chem
; 61(11): 4883-4903, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29767973
20.
Author Correction: A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.
Sci Rep
; 12(1): 17185, 2022 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36229506