Detalhe da pesquisa
1.
Discovery and structure-activity relationship study of 2-piperazinyl-benzothiazole derivatives as potent and selective PPARδ agonists.
Bioorg Med Chem
; 82: 117215, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840990
2.
Discovery and structure-based design of a new series of potent and selective PPARδ agonists utilizing a virtual screening method.
Bioorg Med Chem Lett
; 59: 128567, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35063634
3.
Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure.
J Med Chem
; 66(16): 11428-11446, 2023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552807
4.
Cadmium activates extracellular signal-regulated kinase 5 in HK-2 human renal proximal tubular cells.
Biochem Biophys Res Commun
; 421(3): 490-3, 2012 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22521884
5.
CT Hounsfield Unit Is a Good Predictor of Growth in Meningiomas.
Neurol Med Chir (Tokyo)
; 59(2): 54-62, 2019 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30686812
6.
Circumstances, activities, and events precipitating aneurysmal subarachnoid hemorrhage.
J Stroke Cerebrovasc Dis
; 16(1): 25-9, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17689388
7.
Intracranial localized Castleman's disease. Case report.
Neurol Med Chir (Tokyo)
; 45(1): 59-65, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15699624
8.
Structure-activity relationships of a novel class of endothelin-A receptor antagonists and discovery of potent and selective receptor antagonist, 2-(benzo[1,3]dioxol-5-yl)-6-isopropyloxy-4-(4-methoxyphenyl)-2H-chromene-3-carboxylic acid (S-1255). 1. Study on structure-activity relationships and basic structure crucial for ET(A) antagonism.
J Med Chem
; 45(10): 2041-55, 2002 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-11985472
9.
A novel class of endothelin-A receptor antagonists, (R)-2-(benzo[1,3]dioxol-5-yl)-6-isopropyloxy-2H-chromene-3-carboxylic acids (S-1255). Conformational analysis of basic structure, crucial for ET(A) antagonism, in solution and solid states.
Bioorg Med Chem
; 10(12): 3965-72, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12413848
10.
Practical enantioselective synthesis of endothelin antagonist S-1255 by dynamic resolution of 4-methoxychromene-3-carboxylic acid intermediate.
J Org Chem
; 67(22): 7741-9, 2002 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12398498