Detalhe da pesquisa
1.
Gene Therapy in Combination with Nitrogen Scavenger Pretreatment Corrects Biochemical and Behavioral Abnormalities of Infant Citrullinemia Type 1 Mice.
Int J Mol Sci
; 23(23)2022 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499263
2.
Helper-dependent adenoviral liver gene therapy protects against induced attacks and corrects protein folding stress in acute intermittent porphyria mice.
Hum Mol Genet
; 22(14): 2929-40, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562909
3.
Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.
J Transl Med
; 10: 122, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22704060
4.
Sustained enzymatic correction by rAAV-mediated liver gene therapy protects against induced motor neuropathy in acute porphyria mice.
Mol Ther
; 19(2): 243-50, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20877347
5.
Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice.
Gut
; 60(3): 341-9, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855451
6.
Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates.
Mol Ther
; 18(4): 754-65, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20087317
7.
Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria.
J Hepatol
; 52(3): 417-24, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19815305
8.
Vitamin D-binding protein as a biomarker of active disease in acute intermittent porphyria.
J Proteomics
; 127(Pt B): 377-85, 2015 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25979770
9.
Safety and liver transduction efficacy of rAAV5-cohPBGD in nonhuman primates: a potential therapy for acute intermittent porphyria.
Hum Gene Ther
; 24(12): 1007-17, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24070415
10.
Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse.
PLoS One
; 7(3): e32978, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22412963
11.
MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib.
Mol Cancer Res
; 9(5): 564-76, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21460180
12.
Effect of adeno-associated virus serotype and genomic structure on liver transduction and biodistribution in mice of both genders.
Hum Gene Ther
; 20(8): 908-17, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19419275
13.
Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice.
Hepatology
; 44(3): 623-32, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16941711
14.
Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway.
J Biol Chem
; 280(2): 1112-22, 2005 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15528212
15.
Kinetics of myc-max-mad gene expression during hepatocyte proliferation in vivo: Differential regulation of mad family and stress-mediated induction of c-myc.
Mol Carcinog
; 39(2): 85-90, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14750213