Detalhe da pesquisa
1.
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.
Cell
; 178(6): 1493-1508.e20, 2019 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31474370
2.
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Nature
; 581(7808): 316-322, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32433612
3.
Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma.
Blood
; 142(3): 260-273, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37192303
4.
The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease.
Am J Physiol Gastrointest Liver Physiol
; 321(5): G500-G512, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34494462
5.
Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation.
Gastroenterology
; 156(4): 1082-1097.e11, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30452921
6.
Structural and Functional Attributes of the Interleukin-36 Receptor.
J Biol Chem
; 291(32): 16597-609, 2016 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27307043
7.
Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor.
J Biol Chem
; 290(39): 23997-4006, 2015 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269592
8.
Small molecule Toll-like receptor 7 agonists localize to the MHC class II loading compartment of human plasmacytoid dendritic cells.
Blood
; 117(21): 5683-91, 2011 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21487111
9.
A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding.
J Immunol
; 186(7): 4213-22, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383246
10.
Programmed Cell Death-1 (PD-1) anchoring to the GPI-linked co-receptor CD48 reveals a novel mechanism to modulate PD-1-dependent inhibition of human T cells.
Mol Immunol
; 156: 31-38, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36889184
11.
Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.
mBio
; 14(2): e0298122, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36976016
12.
Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease.
EBioMedicine
; 75: 103758, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34933179
13.
NFAM1 Promotes Pro-Inflammatory Cytokine Production in Mouse and Human Monocytes.
Front Immunol
; 12: 773445, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35095847
14.
Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice.
Respir Res
; 10: 43, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19486528
15.
Co-expression Networks Identify DHX15 RNA Helicase as a B Cell Regulatory Factor.
Front Immunol
; 10: 2903, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31921164
16.
Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA expression data (FANTOM5).
MAbs
; 11(5): 956-964, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31068073
17.
E3 Ubiquitin Ligase RNF125 Activates Interleukin-36 Receptor Signaling and Contributes to Its Turnover.
J Innate Immun
; 10(1): 56-69, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29176319
18.
Down modulation of human TLR3 function by a monoclonal antibody.
Cell Immunol
; 248(2): 103-14, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18048020
19.
Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies.
MAbs
; 9(7): 1143-1154, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28726542
20.
A pathway analysis of poly(I:C)-induced global gene expression change in human peripheral blood mononuclear cells.
Physiol Genomics
; 26(2): 125-33, 2006 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-16554548