Detalhe da pesquisa
1.
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.
EMBO J
; 39(21): e105111, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32945574
2.
Validation of epidermal AMBRA1 and loricrin (AMBLor) as a prognostic biomarker for nonulcerated American Joint Committee on Cancer stage I/II cutaneous melanoma.
Br J Dermatol
; 190(4): 549-558, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38006317
3.
Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual.
CA Cancer J Clin
; 67(6): 472-492, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29028110
4.
Overall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAFV600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, randomised, phase 3 study.
Lancet Oncol
; 24(1): 33-44, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460017
5.
Triplet Therapy in Melanoma - Combined BRAF/MEK Inhibitors and Anti-PD-(L)1 Antibodies.
Curr Oncol Rep
; 24(8): 1071-1079, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35366166
6.
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.
Proc Natl Acad Sci U S A
; 116(36): 17990-18000, 2019 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439820
7.
Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo-controlled, phase 3 trial.
Lancet
; 395(10240): 1835-1844, 2020 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32534646
8.
Impact of initial treatment and prognostic factors on postprogression survival in BRAF-mutated metastatic melanoma treated with dacarbazine or vemurafenib ± cobimetinib: a pooled analysis of four clinical trials.
J Transl Med
; 18(1): 294, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32746839
9.
Impact of depth of response on survival in patients treated with cobimetinib ± vemurafenib: pooled analysis of BRIM-2, BRIM-3, BRIM-7 and coBRIM.
Br J Cancer
; 121(7): 522-528, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31417188
10.
Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.
Blood
; 129(21): 2882-2895, 2017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283481
11.
Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 study.
Lancet Oncol
; 19(5): 672-681, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29602646
12.
Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance.
Int J Cancer
; 142(10): 2139-2152, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29243224
13.
Tumour mutation status and melanoma recurrence following a negative sentinel lymph node biopsy.
Br J Cancer
; 118(10): 1289-1295, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29755118
14.
Health-related quality of life impact of cobimetinib in combination with vemurafenib in patients with advanced or metastatic BRAFV600 mutation-positive melanoma.
Br J Cancer
; 118(6): 777-784, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29438370
15.
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma.
N Engl J Med
; 373(1): 23-34, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26027431
16.
Tumour mutation status and sites of metastasis in patients with cutaneous melanoma.
Br J Cancer
; 117(7): 1026-1035, 2017 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28787433
17.
Health Care Resource Utilization and Associated Costs Among Metastatic Cutaneous Melanoma Patients Treated with Ipilimumab (INTUITION Study).
Oncologist
; 22(8): 951-962, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28526721
18.
Combined vemurafenib and cobimetinib in BRAF-mutated melanoma.
N Engl J Med
; 371(20): 1867-76, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25265494
19.
Checkpoint inhibitors in melanoma and early phase development in solid tumors: what's the future?
J Transl Med
; 15(1): 173, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28789707
20.
Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study.
J Transl Med
; 15(1): 146, 2017 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28646893