Detalhe da pesquisa
1.
Base editing of haematopoietic stem cells rescues sickle cell disease in mice.
Nature
; 595(7866): 295-302, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34079130
2.
Efficient Production of On-Target Reads for Small RNA Sequencing of Single Cells Using Modified Adapters.
Anal Chem
; 90(21): 12609-12615, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30260208
3.
In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs.
Methods
; 103: 167-74, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26972786
4.
Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.
Nucleic Acids Res
; 40(12): 5560-8, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22373919
5.
Identifying functional microRNAs in macrophages with polarized phenotypes.
J Biol Chem
; 287(26): 21816-25, 2012 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22549785
6.
Hepatitis C virus infection and hepatic stellate cell activation downregulate miR-29: miR-29 overexpression reduces hepatitis C viral abundance in culture.
J Infect Dis
; 203(12): 1753-62, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21606534
7.
ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites.
BMC Bioinformatics
; 12: 152, 2011 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21569489
8.
Biliverdin inhibits hepatitis C virus nonstructural 3/4A protease activity: mechanism for the antiviral effects of heme oxygenase?
Hepatology
; 52(6): 1897-905, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21105106
9.
Zinc-finger nucleases as a novel therapeutic strategy for targeting hepatitis B virus DNAs.
Mol Ther
; 18(5): 947-54, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20160705
10.
Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans.
Lab Invest
; 90(12): 1727-36, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20625373
11.
MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling.
Am J Physiol Gastrointest Liver Physiol
; 298(4): G535-41, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20167875
12.
Rational design leads to more potent RNA interference against hepatitis B virus: factors effecting silencing efficiency.
Mol Ther
; 17(3): 538-47, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19088704
13.
Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope.
Nat Commun
; 11(1): 1979, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32332735
14.
The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver.
Mol Ther
; 16(5): 931-41, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18388926
15.
Advances in microRNAs: implications for gene therapists.
Hum Gene Ther
; 19(1): 27-38, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18092919
16.
CleanTag Adapters Improve Small RNA Next-Generation Sequencing Library Preparation by Reducing Adapter Dimers.
Methods Mol Biol
; 1712: 145-161, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29224073
17.
Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification.
Mol Ther Nucleic Acids
; 12: 530-542, 2018 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30195789
18.
Inhibition of hepatitis B virus in mice by RNA interference.
Nat Biotechnol
; 21(6): 639-44, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12740585
19.
Small RNA Library Preparation Method for Next-Generation Sequencing Using Chemical Modifications to Prevent Adapter Dimer Formation.
PLoS One
; 11(11): e0167009, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875576
20.
5' Unlocked Nucleic Acid Modification Improves siRNA Targeting.
Mol Ther Nucleic Acids
; 2: e103, 2013 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23820891