Detalhe da pesquisa
1.
The complete sequence and comparative analysis of ape sex chromosomes.
Nature
; 2024 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38811727
2.
Co-opting regulation bypass repair as a gene-correction strategy for monogenic diseases.
Mol Ther
; 29(11): 3274-3292, 2021 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33892188
3.
The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones.
J Biol Chem
; 293(14): 5134-5149, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29444822
4.
Insulin secretion and Ca2+ dynamics in ß-cells are regulated by PERK (EIF2AK3) in concert with calcineurin.
J Biol Chem
; 288(47): 33824-33836, 2013 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24114838
5.
GCN2 regulates the CCAAT enhancer binding protein beta and hepatic gluconeogenesis.
Am J Physiol Endocrinol Metab
; 305(8): E1007-17, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23900421
6.
The Complete Sequence and Comparative Analysis of Ape Sex Chromosomes.
bioRxiv
; 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38077089
7.
Genetic connectivity and population structure of African savanna elephants (Loxodonta africana) in Tanzania.
Ecol Evol
; 10(20): 11069-11089, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33144949
8.
Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation.
BMC Cell Biol
; 10: 61, 2009 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19732428
9.
PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice.
BMC Cell Biol
; 8: 38, 2007 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-17727724
10.
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.
Mol Cell Biol
; 24(3): 1365-77, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14729979
11.
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses.
Mol Cell Biol
; 23(16): 5651-63, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12897138
12.
The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.
Mol Cell Biol
; 22(19): 6681-8, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12215525
13.
PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.
Biochem J
; 393(Pt 1): 201-9, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16124869
14.
Tryptophan catabolism generates autoimmune-preventive regulatory T cells.
Transpl Immunol
; 17(1): 58-60, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17157218
15.
PERK regulates Gq protein-coupled intracellular Ca2+ dynamics in primary cortical neurons.
Mol Brain
; 9(1): 87, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27716400
16.
PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility.
PLoS One
; 11(9): e0162766, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27627766
17.
Giraffe genome sequence reveals clues to its unique morphology and physiology.
Nat Commun
; 7: 11519, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27187213
18.
Perk gene dosage regulates glucose homeostasis by modulating pancreatic ß-cell functions.
PLoS One
; 9(6): e99684, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24915520
19.
GCN2 in the brain programs PPARγ2 and triglyceride storage in the liver during perinatal development in response to maternal dietary fat.
PLoS One
; 8(10): e75917, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24130751
20.
Hyperthermia induces the ER stress pathway.
PLoS One
; 6(8): e23740, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21876766