Detalhe da pesquisa
1.
A Phase I Dose-Escalation Study of LY3405105, a Covalent Inhibitor of Cyclin-Dependent Kinase 7, Administered to Patients With Advanced Solid Tumors.
Oncologist
; 29(1): e131-e140, 2024 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531083
2.
Addition of ramucirumab or merestinib to standard first-line chemotherapy for locally advanced or metastatic biliary tract cancer: a randomised, double-blind, multicentre, phase 2 study.
Lancet Oncol
; 22(10): 1468-1482, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34592180
3.
Suppression of p53 and p21CIP1/WAF1 reduces arsenite-induced aneuploidy.
Chem Res Toxicol
; 23(2): 357-64, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20000476
4.
A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib.
Oncotarget
; 11(3): 216-236, 2020 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32076484
5.
Achieving Precision Death with Cell-Cycle Inhibitors that Target DNA Replication and Repair.
Clin Cancer Res
; 23(13): 3232-3240, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28331049
6.
Exit from arsenite-induced mitotic arrest is p53 dependent.
Environ Health Perspect
; 114(9): 1401-6, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16966095
7.
The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells.
Mol Cancer Ther
; 11(8): 1781-8, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22653969
8.
Mitotic arrest-associated apoptosis induced by sodium arsenite in A375 melanoma cells is BUBR1-dependent.
Toxicol Appl Pharmacol
; 231(1): 61-7, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18501396
9.
Arsenite-induced mitotic death involves stress response and is independent of tubulin polymerization.
Toxicol Appl Pharmacol
; 230(2): 235-46, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18485433
10.
Sensitivity to sodium arsenite in human melanoma cells depends upon susceptibility to arsenite-induced mitotic arrest.
Toxicol Appl Pharmacol
; 229(2): 252-61, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18328521
11.
p53 suppression of arsenite-induced mitotic catastrophe is mediated by p21CIP1/WAF1.
J Pharmacol Exp Ther
; 318(1): 142-51, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16614167
12.
Arsenite disrupts mitosis and induces apoptosis in SV40-transformed human skin fibroblasts.
Toxicol Appl Pharmacol
; 180(2): 83-91, 2002 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11969375