Detalhe da pesquisa
1.
BRAF Mutations Open Doors for N-Ethyl-N-Nitrosourea-Induced Gliomagenesis.
Am J Pathol
; 186(10): 2551-4, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27543966
2.
Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process.
Proc Natl Acad Sci U S A
; 111(40): E4214-23, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25246577
3.
PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition.
PLoS One
; 13(7): e0200014, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29975751
4.
Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models.
Brain Pathol
; 27(1): 36-50, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26762242
5.
Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.
Neuro Oncol
; 19(9): 1237-1247, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28398584
6.
Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer.
Neuro Oncol
; 19(11): 1481-1493, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28486691
7.
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.
Neuro Oncol
; 19(11): 1469-1480, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379424
8.
Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.
Neuro Oncol
; 18(7): 962-73, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26826202
9.
Contemporary murine models in preclinical astrocytoma drug development.
Neuro Oncol
; 17(1): 12-28, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25246428
10.
Modeling astrocytoma pathogenesis in vitro and in vivo using cortical astrocytes or neural stem cells from conditional, genetically engineered mice.
J Vis Exp
; (90): e51763, 2014 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25146643
11.
Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis.
Neuro Oncol
; 15(10): 1317-29, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23814263