Detalhe da pesquisa
1.
Inherited cancer predisposing mutations in patients with therapy-related myeloid neoplasms.
Br J Haematol
; 200(4): 489-493, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36349721
2.
Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms.
Blood
; 138(9): 790-805, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34473231
3.
The significance of CUX1 and chromosome 7 in myeloid malignancies.
Curr Opin Hematol
; 29(2): 92-102, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084368
4.
Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS.
Blood
; 131(24): 2682-2697, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29592892
5.
The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.
Nucleic Acids Res
; 45(11): 6350-6361, 2017 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28369554
6.
A new self: MHC-class-I-independent natural-killer-cell self-tolerance.
Nat Rev Immunol
; 5(5): 363-74, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15841099
7.
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
Blood
; 121(6): 975-83, 2013 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23212519
8.
The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).
Br J Haematol
; 166(4): 550-6, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24931631
9.
Haploinsufficient Transcription Factors in Myeloid Neoplasms.
Annu Rev Pathol
; 19: 571-598, 2024 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37906947
10.
CUX1 regulates human hematopoietic stem cell chromatin accessibility via the BAF complex.
Cell Rep
; 43(5): 114227, 2024 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38735044
11.
Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells.
Oncogene
; 42(12): 881-893, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36725889
12.
EGR1 Haploinsufficiency Confers a Fitness Advantage to Hematopoietic Stem Cells Following Chemotherapy.
Exp Hematol
; 115: 54-67, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35995095
13.
Genomic studies controvert the existence of the CUX1 p75 isoform.
Sci Rep
; 12(1): 151, 2022 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34997000
14.
Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.
Haematologica
; 101(6): e232-6, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26944478
15.
Venetoclax imparts distinct cell death sensitivity and adaptivity patterns in T cells.
Cell Death Dis
; 12(11): 1005, 2021 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34707089
16.
2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells.
J Exp Med
; 199(9): 1245-54, 2004 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15123744
17.
Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms.
Blood Cancer Discov
; 1(1): 32-47, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32924016
18.
A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
Blood Adv
; 4(4): 599-606, 2020 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32074275
19.
The Harmful Consequences of Increased Fitness in Hematopoietic Stem Cells.
Cell Stem Cell
; 23(5): 634-635, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388419
20.
System for Informatics in the Molecular Pathology Laboratory: An Open-Source End-to-End Solution for Next-Generation Sequencing Clinical Data Management.
J Mol Diagn
; 20(4): 522-532, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29698836