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1.
J Surg Orthop Adv ; 31(1): 1-6, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35377299

RESUMO

Liver disease carries significant risk in total joint arthroplasty (TJA). The authors sought to investigate the complications in hepatitis C virus (HCV) and cirrhosis patients after TJA. PRISMA guidelines extracted ten studies and meta-analytic analysis was performed. Five hundred and twenty-seven patients with liver disease underwent TJA. The complication rate was 38.9%, with 8% infection at 57 months. Cirrhotic patients had higher complication and infection rates compared to HCV patients (p < 0.001, p < 0.039, respectively). Mortality in cirrhosis patients was 17.8% at 36 months. Studies suggested Child Pugh Class A patients had significantly lower complications than Class B or C. One study revealed lower MELD (Model for End-Stage Liver Disease) scores < 10 carry a low mortality risk of 9.8% compared with 32% mortality if MELD score 10 or above. Cirrhosis has significant infection and mortality risk in total hip and knee arthroplasty. Surgeons can risk stratify these patients by MELD score and Child Pugh Class. (Journal of Surgical Orthopaedic Advances 31(1):001-006, 2022).


Assuntos
Artroplastia do Joelho , Doença Hepática Terminal , Hepatite C , Hepacivirus , Hepatite C/complicações , Hepatite C/epidemiologia , Humanos , Cirrose Hepática/complicações , Índice de Gravidade de Doença
2.
Skeletal Radiol ; 50(12): 2449-2457, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34018006

RESUMO

OBJECTIVE: Rapidly progressive idiopathic arthritis of the hip (RPIA) is defined by progressive joint space narrowing of > 2 mm or > 50% within 1 year. Our aims were to assess (a) the occurrence of RPIA after intra-articular steroid injection, and (b) possible risk factors for RPIA including: patient age, BMI, joint space narrowing, anesthetic and steroid selections, bone mineral density, and pain reduction after injection. MATERIALS AND METHODS: A retrospective search of our imaging database identified 1471 patients who had undergone fluoroscopically guided hip injection of triamcinolone acetonide (Kenalog) and anesthetic within a 10-year period. Patient data, including hip DXA results and patient-reported pain scores, were recorded. Pre-injection and follow-up radiographs were assessed for joint space narrowing, femoral head deformity, and markers of osteoarthritis. Osteoarthritis was graded by Croft score. Associations between patient characteristics and outcome variables were analyzed. RESULTS: One hundred six of 1471 injected subjects (7.2%) met the criteria for RPIA. A control group of 161 subjects was randomly selected from subjects who underwent hip injections without developing RPIA. Compared to controls, patients with RPIA were older, had narrower hip joint spaces, and higher Croft scores before injection (p < 0.05). Patients who developed RPIA did not differ from controls in sex, BMI, hip DXA T-score, anesthetic and steroid injectates, or pain improvement after injection. CONCLUSION: We found that approximately 7% of patients undergoing steroid hip injection developed RPIA. More advanced patient age, greater joint space narrowing, and more severe osteoarthritis are risk factors for the development of RPIA after intra-articular steroid injection.


Assuntos
Osteoartrite do Quadril , Corticosteroides/efeitos adversos , Estudos de Coortes , Humanos , Incidência , Injeções Intra-Articulares , Osteoartrite do Quadril/diagnóstico por imagem , Osteoartrite do Quadril/tratamento farmacológico , Osteoartrite do Quadril/epidemiologia , Medição da Dor , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento
3.
J Arthroplasty ; 34(7S): S337-S342, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30642705

RESUMO

BACKGROUND: We sought to understand the mortality rate of periprosthetic joint infection (PJI) of the hip undergoing 2-stage revision for infection. METHODS: Database search, yielding 23 relevant studies, totaled 19,169 patients who underwent revision for total hip PJI. RESULTS: One-year weighted mortality rate was 4.22% after total hip PJI. Five-year mortality was 21.12%. Average age was 65 years. When comparing the national age-adjusted risk of mortality and the reported 1-year mortality risk in this systematic review, the risk of death after total hip PJI is significantly increased (odds ratio 3.58, P < .001). CONCLUSION: The mortality rate during total hip revision for infection is high. When counseling a patient regarding complications of this disease, death should be discussed.


Assuntos
Artroplastia de Quadril/mortalidade , Infecções Relacionadas à Prótese/etiologia , Infecções Relacionadas à Prótese/mortalidade , Reoperação/mortalidade , Idoso , Idoso de 80 Anos ou mais , Artrite Infecciosa/etiologia , Artrite Infecciosa/mortalidade , Artroplastia de Quadril/efeitos adversos , Feminino , Articulação do Quadril/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Mortalidade , Razão de Chances , Reoperação/efeitos adversos , Fatores de Risco
4.
J Arthroplasty ; 33(12): 3783-3788, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30224099

RESUMO

BACKGROUND: Periprosthetic joint infections (PJIs) are fraught with multiple complications including poor patient-reported outcomes, disability, reinfection, disarticulation, and even death. We sought to perform a systematic review asking the question: (1) What is the mortality rate of a PJI of the knee undergoing 2-stage revision for infection? (2) Has this rate improved over time? (3) How does this compare to a normal cohort of individuals? METHODS: We performed a database search in MEDLINE/EMBASE, PubMed, and all relevant reference studies using the following keywords: "periprosthetic joint infection," "mortality rates," "total knee arthroplasty," and "outcomes after two stage revision." Two hundred forty-two relevant studies and citations were identified, and 14 studies were extracted and included in the review. RESULTS: A total of 20,719 patients underwent 2-stage revision for total knee PJI. Average age was 66 years. Mean mortality percentage reported was 14.4% (1.7%-34.0%) with average follow-up 3.8 years (0.25-9 years). One-year mortality rate was 4.33% (3.14%-5.51%) after total knee PJI with an increase of 3.13% per year mortality thereafter (r = 0.76 [0.49, 0.90], P < .001). Five-year mortality was 21.64%. When comparing the national age-adjusted mortality (Actuarial Life Table) and the reported 1-year mortality risk in this meta-analysis, the risk of death after total knee PJI is significantly increased, with an odds ratio of 3.05 (95% confidence interval, 2.69-3.44; P < .001). CONCLUSION: The mortality rate after 2-stage total knee revision for infection is very high. When counseling a patient regarding complications of this disease, death should be discussed.


Assuntos
Artrite Infecciosa/mortalidade , Artroplastia do Joelho/efeitos adversos , Infecções Relacionadas à Prótese/mortalidade , Reoperação/mortalidade , Artrite Infecciosa/etiologia , Artroplastia do Joelho/mortalidade , Humanos , Articulação do Joelho , Razão de Chances , Infecções Relacionadas à Prótese/etiologia
5.
AJR Am J Roentgenol ; 208(6): W208-W215, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28267356

RESUMO

OBJECTIVE: Our objective was to determine the association between muscle cross-sectional area and attenuation, as measured on routine CT scans, and mortality in older patients with hip fracture. MATERIALS AND METHODS: A retrospective 10-year study of patients with hip fracture was conducted with the following inclusion criteria: age 65 years or older, first-time hip fracture treated with surgery, and CT of the chest, abdomen, or pelvis. This yielded 274 patients (70.4% women; mean [± SD] age, 81.3 ± 8.3 years). On each CT scan, two readers independently measured the size (cross-sectional area, indexed for patient height) and attenuation of the paravertebral muscle at T12 and the psoas muscle at L4. We then determined the association between overall mortality and the muscle size and muscle attenuation, while adjusting for demographic variables (age, sex, ethnicity, and body mass index), American Society of Anesthesiologists (ASA) classification, and Charlson comorbidity index (CCI). RESULTS: The overall mortality rate increased from 28.3% at 1 year to 79.5% at 5 years. Mortality was associated with decreased thoracic muscle size (odds ratio [OR], 0.66; 95% CI, 0.49-0.87). This association persisted after adjusting for demographic variables (OR, 0.69; 95% CI, 0.50-0.95), the ASA classification (OR, 0.70; CI, 0.51-0.97), and the CCI (OR, 0.72; 95% CI, 0.52-1.00). Similarly, decreased survival was associated with decreased thoracic muscle attenuation after adjusting for all of these combinations of covariates (OR, 0.67-0.72; 95% CI, 0.49-0.99). Decreased lumbar muscle size and attenuation trended with decreased survival but did not reach statistical significance. CONCLUSION: In older adults with hip fractures, CT findings of decreased thoracic paravertebral muscle size and attenuation are associated with decreased overall survival.


Assuntos
Fraturas do Quadril/diagnóstico por imagem , Fraturas do Quadril/mortalidade , Sarcopenia/diagnóstico por imagem , Sarcopenia/mortalidade , Análise de Sobrevida , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Idoso de 80 Anos ou mais , California/epidemiologia , Causalidade , Comorbidade , Feminino , Fraturas do Quadril/cirurgia , Humanos , Masculino , Tamanho do Órgão , Prevalência , Modelos de Riscos Proporcionais , Reprodutibilidade dos Testes , Estudos Retrospectivos , Medição de Risco , Sarcopenia/cirurgia , Sensibilidade e Especificidade
6.
J Arthroplasty ; 32(5): 1665-1669, 2017 05.
Artigo em Inglês | MEDLINE | ID: mdl-28012720

RESUMO

BACKGROUND: The sacro-femoral-pubic (SFP) parameter, calculated using the SFP angle measured on a frontal pelvis radiograph, has previously been shown to have a strong correlation with sagittal pelvic tilt (PT) measured on a lateral x-ray. The purpose of this study is to assess the validity, interobserver reliability and intraobserver reproducibility of the SFP parameter in predicting the sagittal PT. METHODS: This is a retrospective study of 100 patients with frontal and lateral radiographs of the pelvis. Two observers independently measured the SFP angle on frontal x-ray (midpoint of S1 end plate to centroid of acetabula to upper midpoint of the pubic symphysis) and PT on lateral x-ray (midpoint of sacral plate to the centroid of acetabula to vertical plane). The SFP parameter was defined using the equation: SFP parameter = 75 - SFP angle. The interobserver reliability and intraobserver reproducibility were calculated using interclass correlation coefficient (ICC). Validity of the SFP parameter was calculated using Pearson correlation coefficient. RESULTS: The intraobserver reproducibility of the SFP parameter was excellent (ICC >0.90) for both observers. The interobserver reliability of all measurements was substantial for the SFP parameter (ICC >0.80) and PT (ICC >0.70). The concurrent validity of the SFP parameter was substantial (r = 0.70). CONCLUSION: Calculating PT from a frontal radiograph using the equation for the SFP parameter is a valid, reliable, and reproducible formula that may be used to predict sagittal PT.


Assuntos
Artroplastia de Quadril , Fêmur/diagnóstico por imagem , Pelve/diagnóstico por imagem , Osso Púbico/diagnóstico por imagem , Sacro/diagnóstico por imagem , Acetábulo , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Placas Ósseas , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Radiografia , Reprodutibilidade dos Testes , Estudos Retrospectivos , Raios X , Adulto Jovem
7.
J Am Acad Orthop Surg ; 32(13): 597-603, 2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38236919

RESUMO

BACKGROUND: The incidence and time course of acute venous thromboembolism (VTE) after ambulatory surgery for lower extremity orthopaedic conditions is not well-defined. HYPOTHESIS: The purpose of this study was to analyze the incidence, the time course, and risk factors associated with clinically diagnosed acute deep vein thrombosis or pulmonary embolism within 3 months of surgery in patients undergoing specific operations for lower extremity injuries. METHODS: Patients undergoing arthroscopic procedures of the knee, ankle fracture surgery, Achilles tendon repair, and ankle arthroscopy from January 1, 2005, to December 31, 2010, were identified in the California Ambulatory Surgery database with linkage to hospital discharge data, emergency department data, and a death registry. Outcomes were acute VTE and death within 90 days. Time courses were compared using Kaplan-Meier analysis, and risk factors were analyzed using proportional hazard modeling. RESULTS: Analysis of data from 468,699 surgeries showed that the cumulative incidence of acute VTE was significantly higher after Achilles tendon repair (0.72%, P < 0.001) than ankle fracture surgery (0.33%), knee arthroscopy procedures (range, 0.29% to 0.41%), or ankle arthroscopy (0.24%). The time course of diagnosis of VTE was similar for all arthroscopic procedures (median postoperative day for diagnosis = 9 to 10; 80% by 22 to 36 days), whereas for Achilles tendon surgery, the time course was protracted (median postoperative day for diagnosis = 29 days; 80% by 51 days). Ninety-day mortality was low (<0.06%) after all procedures except ankle fracture (0.12%). Predictors of pulmonary embolism included age older than 60 years (HR, 3.1; 95% CI; 2.0 to 4.8, versus younger than 30 years), Achilles tendon repair (HR, 3.8; 95% CI; 2.8 to 5.3), and ankle fracture surgery (Hazard Ratio [HR], 2.1; 95% Confidence Interval [CI]; 1.5 to 2.8); Asian/Pacific Islander (HR, 0.3; 95% CI; 0.1 to 0.6) and Hispanic patients (HR, 0.5; 95% CI; 0.4 to 0.7) had significantly lower risk. DISCUSSION: The incidence and time course of onset of acute VTE after lower extremity orthopaedic surgeries varies significantly depending on the surgical procedure. These findings have implications regarding the use and duration of pharmacologic thromboprophylaxis.


Assuntos
Tendão do Calcâneo , Fraturas do Tornozelo , Artroscopia , Complicações Pós-Operatórias , Embolia Pulmonar , Humanos , Tendão do Calcâneo/cirurgia , Tendão do Calcâneo/lesões , Incidência , Masculino , Feminino , Pessoa de Meia-Idade , Fraturas do Tornozelo/cirurgia , Adulto , Embolia Pulmonar/epidemiologia , Embolia Pulmonar/etiologia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Idoso , Fatores de Risco , Fatores de Tempo , Tromboembolia Venosa/epidemiologia , Tromboembolia Venosa/etiologia , Trombose Venosa/epidemiologia , Trombose Venosa/etiologia , Adulto Jovem
8.
Artigo em Inglês | MEDLINE | ID: mdl-38648392

RESUMO

BACKGROUND: Opioid use after revision total hip arthroplasty (rTHA) has not been well characterized. The purpose of this study was to characterize preoperative, perioperative, and postoperative opioid use during rTHA. METHODS: Patients undergoing revision THA from 2010 to 2018 were screened for opioid use 3 months before revision surgery and tracked 24 months postoperatively. Patients were categorized as naïve or tolerant. Opioid prescriptions and average morphine milligram equivalents (MME) were compared between the two groups. RESULTS: One hundred twenty-four of 247 patients (50%) in the tolerant group averaged a preoperative MME of 23.7 mg/day. Postoperatively, tolerant patients received significantly higher daily MME at all time points, including at 3 months 31.4 versus 18.1 mg/day (P < 0.001), 6 months 19.9 versus 2.95 mg/day (P < 0.001), 12 months 14.3 versus 3.5 mg/day (P < 0.001), and 24 months 10.7 versus 2.17 mg/day (P < 0.001). Tolerant patients were more likely to have a prescription at 6 months (44% versus 22%), 12 months (41.4% versus 24%), and 24 months (38% versus 19.3%) (P < 0.001, P = 0.002, P < 0.001, respectively). DISCUSSION: Opioid-tolerant patients had higher postoperative MME requirements for longer recovery duration. Both groups reduced opioid use at 3 months and plateaued at 6 months. These findings can help the revision surgeon counsel patients and expectations.


Assuntos
Analgésicos Opioides , Artroplastia de Quadril , Dor Pós-Operatória , Reoperação , Humanos , Analgésicos Opioides/uso terapêutico , Masculino , Feminino , Dor Pós-Operatória/tratamento farmacológico , Pessoa de Meia-Idade , Idoso , Tolerância a Medicamentos , Estudos Retrospectivos
9.
Clin Orthop Relat Res ; 471(11): 3581-7, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23922189

RESUMO

BACKGROUND: Cam morphology in femoroacetabular impingement has been implicated in the development of osteoarthritis. The alpha angle and femoral head/neck offset are widely used to determine femoral head asphericity. To our knowledge, no study has evaluated the alpha angle circumferentially using three-dimensional imaging in a population of healthy individuals of adolescent age. QUESTIONS/PURPOSES: We sought to (1) determine normal values for the alpha angle in adolescents, (2) define the location along the neck with the highest alpha angle, and (3) determine normal femoral head and neck radii and femoral head/neck offset. METHODS: Fifty CT scans from a database of scans obtained for reasons not related to hip pain were studied. The average age of the subjects was 15 years (range, 14-16 years). Alpha angle and femoral head/neck offset were measured circumferentially. RESULTS: The alpha angle averaged 40.66 ± 4.46 mm for males and 37.77 ± 5.65 mm for females. The alpha angle generally was highest between the 11:40 and 12:40 o'clock and between the 6:00 and 7:40 o'clock positions. The femoral head radius was 24.53 ± 1.74 mm for males and 21.94 ± 1.13 mm for females, and the femoral neck radius was 16.14 ± 2.32 mm for males and 13.82 ± 2.38 mm for females. The mean femoral head/neck offset was 8.39 ± 1.97 mm for males and 8.13 ± 2.27 mm for females. CONCLUSIONS: In this healthy population of 14- to 16-year-old subjects, the highest alpha angle was at the superior and inferior aspects of the heads rather than at the anterosuperior aspect. This information will provide benchmark values for distinction between normal and abnormal morphologic features of the femoral head.


Assuntos
Cabeça do Fêmur/diagnóstico por imagem , Colo do Fêmur/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adolescente , Fatores Etários , Feminino , Humanos , Imageamento Tridimensional , Masculino , Interpretação de Imagem Radiográfica Assistida por Computador , Valores de Referência , Fatores Sexuais
10.
J Arthroplasty ; 28(8): 1386-90, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23535286

RESUMO

The objective of this study was to evaluate the most common treatments performed for hip fractures over the last decade in the United States. The leading treatment for trochanteric fractures was internal fixation, accounting for 96%-98% of surgical treatments each year. For cervical fractures, hemiarthroplasty (HA), total hip arthroplasty (THA), and internal fixation were performed nearly 61%, 5%, and 33% of the time, respectively, each year without any sign of change during the period assessed. The surgical choice for cervical fractures varied greatly by patient age. In 2009, two-thirds of patients younger than 60 years underwent internal fixation while two-thirds of patients 60 years or older underwent HA. Regardless of patient age, HA was performed more often than THA for cervical hip fractures.


Assuntos
Artroplastia de Quadril/tendências , Fraturas do Fêmur/cirurgia , Fixação Interna de Fraturas/tendências , Hemiartroplastia/tendências , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Artroplastia de Quadril/métodos , Artroplastia de Quadril/estatística & dados numéricos , Fraturas do Fêmur/epidemiologia , Fraturas do Colo Femoral/epidemiologia , Fraturas do Colo Femoral/cirurgia , Fêmur/lesões , Fêmur/cirurgia , Colo do Fêmur/lesões , Colo do Fêmur/cirurgia , Fixação Interna de Fraturas/métodos , Fixação Interna de Fraturas/estatística & dados numéricos , Hemiartroplastia/métodos , Hemiartroplastia/estatística & dados numéricos , Fraturas do Quadril/epidemiologia , Fraturas do Quadril/cirurgia , Humanos , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Estados Unidos/epidemiologia
11.
World J Orthop ; 14(3): 90-102, 2023 Mar 18.
Artigo em Inglês | MEDLINE | ID: mdl-36998388

RESUMO

As the number of patients receiving total joint replacements continues to rise, considerable attention has been directed towards the early detection and prevention of postoperative complications. While D-dimer has long been studied as a diagnostic tool in venous thromboembolism (VTE), this assay has recently received considerable attention in the diagnosis of periprosthetic joint infection (PJI). D-dimer values are substantially elevated in the acute postoperative period after total joint arthroplasty, with levels often exceeding the standard institutional cutoff for VTE (500 µg/L). The utility of D-dimer in detecting VTE after total joint replacement is currently limited, and more research to assess its value in the setting of contemporary prophylaxis protocols is warranted. Recent literature supports D-dimer as a good to excellent biomarker for the diagnosis of chronic PJI, especially when using serum sample technique. Providers should exercise caution when interpreting D-dimer levels in patients with inflammatory and hypercoagulability disorders, as the diagnostic value is decreased. The updated 2018 Musculoskeletal Infection Society criteria, which includes D-dimer levels > 860 µg/L as a minor criterion, may be the most accurate for diagnosing chronic PJI to date. Larger prospective trials with transparent lab testing protocols are needed to establish best assay practices and optimal cutoff values for D-dimer in the diagnosis of PJI. This review summarizes the most current literature on the value of D-dimer in total joint arthroplasty and elucidates areas for future progress.

12.
Arthroplast Today ; 21: 101123, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37012932

RESUMO

Coccidioidomycosis is a fungal infection endemic to certain regions of the Americas. In some cases, the organism may infect the musculoskeletal system, resulting in a prosthetic joint infection (PJI). Due to its difficulty in diagnosis, treatment of coccidioidomycosis in PJI is often delayed. Furthermore, with limited number of case reports, a standard of care in treatment has yet to be established. We present 2 cases of coccidioidomycosis PJI, the extensive evaluation that led to the diagnosis, and the treatment provided. This report highlights the natural progression of coccidioidomycosis in a prosthetic joint, the diagnostic features including histology, advanced imaging, and final treatment administered.

13.
Artigo em Inglês | MEDLINE | ID: mdl-37027225

RESUMO

INTRODUCTION: Controversy exists on the ideal type of fixation in total knee arthroplasty (TKA). Noncemented fixation has been theorized to improve patient outcomes and longevity of implantation without increased risk of aseptic loosening or radiolucent lines. We sought to compare (1) patient-reported outcomes, (2) survivorship, and (3) revision rates for all-cause and aseptic loosening in a noncemented tantalum total knee with its cemented counterpart. METHODS: Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines were searched using a combination of keywords "trabecular metal," "tantalum knee," "total knee arthroplasty," and "cementless trabecular." Patient demographics such as age, sex, and body mass index were collected. Outcomes such as Knee Society Scores (KSSs), revisions, and radiolucent lines were recorded for analysis. RESULTS: Four randomized controlled trials involving 507 patients with an average 5-year follow-up were eligible for meta-analysis. No differences were observed in any demographics such as age, sex, body mass index, nor preoperative KSS. Patients in the cemented cohort improved from preoperative KSS 46.4 to postoperative KSS 90.4 while the tantalum cohort improved from 46.4 to 89.3. No statistical difference was observed in postoperative KSS mean difference between groups. Six patients from the tantalum group underwent revision with one patient for aseptic loosening. Twelve patients from the cemented group underwent revision with four patients for aseptic loosening. No statistical difference was observed between rates of revision, aseptic loosening, or radiolucent line development. DISCUSSION: Patient-reported outcomes improved postoperatively in both groups. No differences were detected between the cemented and noncemented TKAs in patient-reported outcomes, revision rates, or radiolucent line development. Noncemented tantalum fixation seems equivalent to cemented TKA survivorship. Longer term follow-up of these randomized controlled trials may provide a clearer understanding whether a difference exists.


Assuntos
Artroplastia do Joelho , Prótese do Joelho , Humanos , Tantálio , Reoperação , Cimentos Ósseos/uso terapêutico
14.
Cureus ; 15(8): e43768, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37727155

RESUMO

Purpose Enhanced recovery protocols for total hip arthroplasty (THA), using opioid-sparing techniques have become widely used. Reports of novel additions to multimodal pain control regimens have been published, however, a paucity of literature exists on the use of intravenous dexmedetomidine. In this study, we analyzed our experience with intravenous dexmedetomidine and hypothesized that it would reduce postoperative opioid use. Secondary outcomes were also examined, including post-operative hypotension, hemoglobin, length of stay, and discharge disposition. Methods All patients who underwent primary THA at a single tertiary-level center between January 1, 2016, and September 1, 2019, underwent investigation. Diagnosis, surgical approach, anesthetic type, body mass index (BMI), and American Society of Anesthesiologists (ASA) score were recorded. Postoperative clinical measures were analyzed, adjusting for patient and surgical characteristics. Results Of the 599 patients included in the study, 218 patients received intravenous (IV) dexmedetomidine, at a mean dose of 44.9 mg during their operative event. Using a multivariate model, patients in the IV dexmedetomidine group were estimated to have received 24% elevated morphine milligram equivalent at postoperative day zero compared to those in the control group (p = 0.05). In addition, patients in the IV dexmedetomidine group who underwent spinal anesthesia had increased odds of hypotension 3.47 times that of the control [odds ratio (OR) 1.43-8.43, p=0.006]. Conclusions Surprisingly, we found no opioid-sparing effects with the use of IV dexmedetomidine. IV dexmedetomidine may be used cautiously as an anesthesia adjunct with spinal anesthesia in the setting of primary THA, as the experience at our institution illustrated increased odds of postoperative hypotension. Level of evidence This retrospective case-control study has a level of evidence III.

15.
Artigo em Inglês | MEDLINE | ID: mdl-37167581

RESUMO

INTRODUCTION: Single-stage revision arthroplasty for periprosthetic joint infection (PJI) may yield comparable infection-free survivorship with two-stage revision arthroplasty. It is unclear if the most common mode of failure of single-stage revision arthroplasty is infection or aseptic loosening. In this meta-analysis, we sought to (1) determine survivorship and (2) compare rates of different etiologies of failure of single-stage revision total hip arthroplasty (THA) and total knee arthroplasty (TKA). METHODS: Preferred Reporting Items for Systematic Review and Meta-analyses guidelines search was done using search terms for "single stage revision," "exchange arthroplasty," "periprosthetic infection," "PJI," and "single stage." Patient demographics such as age, body mass index, and mean follow-up time were recorded. Overall survivorship and rates of revision surgery were aggregated using a random-effects model. Comparison of septic and aseptic loosening rates was done by risk difference and associated 95% confidence interval (CI) calculation. RESULTS: Twenty-four studies were identified with 2,062 and 147 single-stage revision THA and TKA procedures performed between 1984 and 2019, respectively. The weighted mean follow-up and age were 69.8 months and 66.3 years, respectively, with 55% men overall. The all-cause revision surgery rate was 11.1% and 11.8% for THA and TKA, respectively. The revision surgery rate secondary to infection and aseptic loosening and associated 95% CI for the risk difference for THA and TKA was 5.5% and 3.3% (-1.7% to 5.0%), and 3% and 8.8% (-11.4% to 2.3%), respectively. Revision surgeries due to instability and fracture combined and mortality rate were both less than 3%. DISCUSSION: Single-stage revision THA and TKA for PJI demonstrated overall high rates of survivorship, low mortality, and revision surgeries secondary to infection and aseptic loosening to be equivalent. Aseptic loosening after single-stage revision TKA might be higher than in primary TKA. As implant survivorship from infection improves in PJI, surgeons should be aware of aseptic loosening as an equally common mode of failure.


Assuntos
Artrite Infecciosa , Artroplastia de Quadril , Artroplastia do Joelho , Infecções Relacionadas à Prótese , Masculino , Humanos , Feminino , Infecções Relacionadas à Prótese/etiologia , Infecções Relacionadas à Prótese/cirurgia , Sobrevivência , Falha de Prótese , Artroplastia do Joelho/efeitos adversos , Artroplastia de Quadril/efeitos adversos , Artrite Infecciosa/etiologia , Artrite Infecciosa/cirurgia
16.
J Arthroplasty ; 27(10): 1777-82, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22868071

RESUMO

The objective of this study was to describe the trend in utilization of primary joint arthroplasties in Germany. Between 2004 and 2008, the number of total knee arthroplasties (TKAs) increased faster than that of total hip arthroplasties (THAs). In 2008, 159000 primary THAs and 146000 primary TKAs were performed. This represented a 15% increase in THAs and a 33% increase in TKAs compared to 2004. The annual increase in number of surgeries was 4500 for THAs and 9,000 for TKAs. Although older adults remained the main recipients of joint arthroplasties, incidence rate increased faster in non-elderly(18-64 years) compared with elderly (≥65 years) in both THAs and TKAs. Obesity, more strongly associated with TKAs than with THAs, could be a contributor to the recent steeper growth in TKAs in Germany.


Assuntos
Artroplastia de Quadril/estatística & dados numéricos , Artroplastia do Joelho/estatística & dados numéricos , Adolescente , Adulto , Idoso , Alemanha , Humanos , Pessoa de Meia-Idade , Obesidade/complicações
17.
J Arthroplasty ; 26(8): 1198-204, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-21392934

RESUMO

To find a safer surgical option, a number of studies have compared postoperative complications after bilateral total knee arthroplasty vs staged total knee arthroplasty (STKA) by contrasting postoperative complications collected retrospectively. However, we believe that a comparison based on retrospective studies could be biased. The purpose of this study was to demonstrate the misclassification bias associated with a retrospective study in comparing operative outcomes. Our analysis indicates that any conclusions based simply on retrospective analysis of subjects who successfully completed STKA is biased because it includes only cases that recovered after the first operation, rather than all of the patients who had planned STKA. In the absence of a prospective study to date, published studies should be interpreted with caution.


Assuntos
Artroplastia do Joelho/efeitos adversos , Artroplastia do Joelho/estatística & dados numéricos , Articulação do Joelho/cirurgia , Osteoartrite do Joelho/cirurgia , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Viés , Humanos , Modelos Teóricos , Viés de Publicação , Fatores de Risco , Resultado do Tratamento , Estados Unidos
18.
J Arthroplasty ; 26(6): 976.e17-20, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21856500

RESUMO

In the setting of extraarticular deformities of the knee, total knee arthroplasty (TKA) is difficult, as anatomical abnormalities obstruct identification of alignment landmarks and may preclude the use of traditional instrumentation. The long-term clinical value of computer assistance for TKA is a point of ongoing controversy. Few reports describe the use of computer-assisted orthopedic surgery as a method to decrease alignment outliers in TKA with associated posttraumatic deformities. In this report, a 70-year-old woman who had a severe distal femoral deformity from a previous open fracture underwent computer-assisted TKA for osteoarthritis. The use of a computer-assisted navigation system achieved a high degree of accuracy relative to the desired target alignment and led to improved function in a patient in which standard instrumentation was not feasible.


Assuntos
Artroplastia do Joelho/métodos , Fêmur/lesões , Deformidades Articulares Adquiridas/etiologia , Osteoartrite do Joelho/cirurgia , Cirurgia Assistida por Computador/métodos , Ferimentos e Lesões/complicações , Idoso , Artroplastia do Joelho/instrumentação , Mau Alinhamento Ósseo/prevenção & controle , Feminino , Fêmur/diagnóstico por imagem , Fêmur/cirurgia , Humanos , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/cirurgia , Prótese do Joelho , Radiografia , Resultado do Tratamento
19.
J Arthroplasty ; 26(8): 1451-4, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-21497483

RESUMO

This study is a retrospective evaluation of the intermediate-term results of 26 consecutive revision total hip arthroplasties performed with a modular titanium, uncemented femoral component. The average patient age at the time of revision total hip arthroplasty was 72 years, and there were an equal number of males and females. The mean follow-up was 5.7 years (ranging from 4 to 11 years). No re-revision was necessary during this follow-up time. The mean Harris hip score improved significantly (preoperative and postoperative score was 50.7 and 89.6, respectively; P < .001). Postoperatively, Short Form 36 functional scores averaged 67.7 across 9 functional parameters. Our observed low revision rate and favorable patient-reported outcome scores support the continuous use of modular titanium, uncemented femoral components in revision total hip arthroplasty.


Assuntos
Artroplastia de Quadril/instrumentação , Fêmur , Articulação do Quadril/diagnóstico por imagem , Articulação do Quadril/cirurgia , Prótese de Quadril , Desenho de Prótese , Titânio , Idoso , Idoso de 80 Anos ou mais , Artroplastia de Quadril/métodos , Feminino , Seguimentos , Articulação do Quadril/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Porosidade , Falha de Prótese , Radiografia , Amplitude de Movimento Articular/fisiologia , Reoperação , Estudos Retrospectivos , Resultado do Tratamento
20.
Arthroscopy ; 26(1): 121-7, 2010 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-20117636

RESUMO

We present 2 cases of cam/pincer combined femoroacetabular impingement treated arthroscopically with labral debridement, acetabuloplasty, and femoral head recontouring. In both cases there was essentially no evidence of osteoarthritis of the hip. However, in both cases raised exostoses were evident on the anterolateral femoral neck in the region that commonly comes into contact with the acetabular rim. On the basis of 3-dimensional dynamic reconstructions, we surmise that these exostoses are a direct result of linear contact between the femoral neck and acetabular rim. We recommend that the presence of these exostoses be carefully noted by the arthroscopic hip surgeon and that they be a geographic marker of the zone of contact between the head-neck junction and the acetabular rim and a guide for the area of head osteochondroplasty in combination with appropriate treatment of the acetabular rim.


Assuntos
Acetábulo/patologia , Artralgia/etiologia , Cartilagem Articular/patologia , Exostose/etiologia , Colo do Fêmur/patologia , Articulação do Quadril/patologia , Acidentes por Quedas , Acetábulo/diagnóstico por imagem , Acetábulo/cirurgia , Adolescente , Artralgia/cirurgia , Artroscopia/métodos , Desbridamento/métodos , Exostose/diagnóstico por imagem , Exostose/cirurgia , Feminino , Colo do Fêmur/diagnóstico por imagem , Colo do Fêmur/cirurgia , Fluoroscopia , Fricção , Articulação do Quadril/cirurgia , Humanos , Imageamento Tridimensional , Masculino , Artes Marciais/lesões , Pessoa de Meia-Idade , Ossos Pélvicos/diagnóstico por imagem , Radiografia Intervencionista , Tomografia Computadorizada por Raios X
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