Detalhe da pesquisa
1.
Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1.
Biochim Biophys Acta
; 1789(5): 422-31, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19414071
2.
Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.
Can J Physiol Pharmacol
; 88(6): 682-91, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20628435
3.
Darusentan is a potent inhibitor of endothelin signaling and function in both large and small arteries.
Can J Physiol Pharmacol
; 88(8): 840-9, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20725142
4.
A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway.
Proc Natl Acad Sci U S A
; 101(9): 2870-5, 2004 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-14976250