Detalhe da pesquisa
1.
A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally advanced or metastatic solid tumors.
Invest New Drugs
; 39(1): 163-174, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737717
2.
A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors.
Cancer Discov
; 7(1): 102-113, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27872130
3.
A randomized controlled trial of a cardiopulmonary resuscitation video in advance care planning for progressive pancreas and hepatobiliary cancer patients.
J Palliat Med
; 16(6): 623-31, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23725233
4.
gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.
Cancer Res
; 69(2): 573-82, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19147571