Detalhe da pesquisa
1.
Emerging Role of GLP-1 Agonists in Obesity: A Comprehensive Review of Randomised Controlled Trials.
Int J Mol Sci
; 24(13)2023 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37445623
2.
Diabetes Mellitus Secondary to Endocrine Diseases: An Update of Diagnostic and Treatment Particularities.
Int J Mol Sci
; 24(16)2023 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37628857
3.
The Unusual Architecture of RNA-Dependent RNA Polymerase (RdRp)'s Catalytic Chamber Provides a Potential Strategy for Combination Therapy against COVID-19.
Molecules
; 28(6)2023 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36985777
4.
Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study.
Bioorg Med Chem Lett
; 27(20): 4760-4764, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28935265
5.
Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives.
J Enzyme Inhib Med Chem
; 31(6): 1694-7, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26899668
6.
Revolutionizing Treatment Strategies for Autoimmune and Inflammatory Disorders: The Impact of Dipeptidyl-Peptidase 4 Inhibitors.
J Inflamm Res
; 17: 1897-1917, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38544813
7.
Pyrrolo[2,3-d]pyrimidines as EGFR and VEGFR kinase inhibitors: a comprehensive SAR review.
Curr Med Chem
; 2023 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37581522
8.
Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi.
Microb Biotechnol
; 16(11): 2053-2071, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37804207
9.
Investigation of Simultaneous and Sequential Cooperative Homotropic Inhibitor Binding to the Catalytic Chamber of SARS-CoV-2 RNA-dependent RNA Polymerase (RdRp).
Cell Biochem Biophys
; 81(4): 697-706, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37658974
10.
Corrigendum to "Synthesis and biological activity of 2,5-diaryl-3-methylpyrimido[4,5-c]quinolin-1(2H)-one derivatives" [Bioorg. Med. Chem. 15 (2007) 2434-2440].
Bioorg Med Chem
; 25(9): 2679, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28341404
11.
Neuroprotective Effects of Phytochemicals against Aluminum Chloride-Induced Alzheimer's Disease through ApoE4/LRP1, Wnt3/ß-Catenin/GSK3ß, and TLR4/NLRP3 Pathways with Physical and Mental Activities in a Rat Model.
Pharmaceuticals (Basel)
; 15(8)2022 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36015156
12.
Profiling the physiological pitfalls of anti-hepatitis C direct-acting agents in budding yeast.
Microb Biotechnol
; 14(5): 2199-2213, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378349
13.
Synthesis, in-vitro cytotoxicity, and a preliminary structure-activity relationship investigation of pyrimido[4,5-c]quinoline-1(2H)-ones.
Arch Pharm (Weinheim)
; 343(8): 465-72, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20803623
14.
A novel scaffold to fight Pseudomonas aeruginosa pyocyanin production: early steps to novel antivirulence drugs.
Future Med Chem
; 12(16): 1489-1503, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32772556
15.
Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells.
Chem Biol Interact
; 306: 123-130, 2019 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30958995
16.
Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase.
Eur J Med Chem
; 152: 160-174, 2018 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29705708
17.
Pyrimido[4,5-c]quinolin-1(2H)-ones as a novel class of antimitotic agents: Synthesis and in vitro cytotoxic activity.
Eur J Med Chem
; 42(3): 344-50, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17141923
18.
Non-carboxylic analogues of arylpropionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential.
Eur J Med Chem
; 42(2): 152-60, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17052805
19.
Novel 2,4- thiazolidinediones: Synthesis, in vitro cytotoxic activity, and mechanistic investigation.
Eur J Med Chem
; 133: 340-350, 2017 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28395220
20.
Synthesis and anticancer activity of novel quinazolinone-based rhodanines.
Chem Cent J
; 11(1): 102, 2017 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29086906