Detalhe da pesquisa
1.
A biparatopic agonistic antibody that mimics fibroblast growth factor 21 ligand activity.
J Biol Chem
; 293(16): 5909-5919, 2018 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483191
2.
Anti-PCSK9 antibody pharmacokinetics and low-density lipoprotein-cholesterol pharmacodynamics in nonhuman primates are antigen affinity-dependent and exhibit limited sensitivity to neonatal Fc receptor-binding enhancement.
J Pharmacol Exp Ther
; 353(1): 119-31, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25653417
3.
Targeted codon optimization improves translational fidelity for an Fc fusion protein.
Biotechnol Bioeng
; 109(11): 2770-7, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22573571
4.
Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes.
PLoS One
; 7(11): e49345, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23209571