Detalhe da pesquisa
1.
Physiological temperatures reduce dimerization of dengue and Zika virus recombinant envelope proteins.
J Biol Chem
; 293(23): 8922-8933, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29678884
2.
Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses.
Bioconjug Chem
; 29(5): 1544-1552, 2018 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29701995
3.
Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.
Mol Hum Reprod
; 22(6): 410-26, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26921398
4.
Computational design of a symmetric homodimer using ß-strand assembly.
Proc Natl Acad Sci U S A
; 108(51): 20562-7, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22143762
5.
Functional characterization of the multidomain F plasmid TraI relaxase-helicase.
J Biol Chem
; 286(14): 12670-82, 2011 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21288910
6.
Structural determinants of affinity enhancement between GoLoco motifs and G-protein alpha subunit mutants.
J Biol Chem
; 286(5): 3351-8, 2011 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21115486
7.
Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer.
J Am Chem Soc
; 134(1): 375-85, 2012 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22092237
8.
Structural basis for the restoration of TCR recognition of an MHC allelic variant by peptide secondary anchor substitution.
J Exp Med
; 200(11): 1445-54, 2004 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15557346
9.
The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.
Drug Metab Rev
; 42(1): 133-44, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19821783
10.
Oligomeric state of the ZIKV E protein defines protective immune responses.
Nat Commun
; 10(1): 4606, 2019 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31601808
11.
Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7.
J Mol Biol
; 369(2): 498-511, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17442341
12.
The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.
Drug Metab Dispos
; 36(3): 517-22, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18048489
13.
P-glycoprotein targeted photodynamic therapy of chemoresistant tumors using recombinant Fab fragment conjugates.
Biomater Sci
; 6(11): 3063-3074, 2018 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30298866
14.
Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype.
PLoS Negl Trop Dis
; 12(9): e0006793, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30248097
15.
Dissecting the human serum antibody response to secondary dengue virus infections.
PLoS Negl Trop Dis
; 11(5): e0005554, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28505154
16.
In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers.
Sci Rep
; 7(1): 4524, 2017 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28674411
17.
Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.
ChemMedChem
; 12(3): 207-213, 2017 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28032464
18.
Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses.
PLoS Negl Trop Dis
; 10(10): e0005071, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27764114
19.
Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors.
ACS Med Chem Lett
; 7(12): 1044-1049, 2016 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27994735
20.
The role of mhc polymorphism in anti-microbial resistance.
Microbes Infect
; 6(5): 501-12, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15109966