Detalhe da pesquisa
1.
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Mol Cell
; 80(6): 996-1012.e9, 2020 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33147438
2.
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.
Nature
; 600(7887): 158-163, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34819667
3.
Efficient Synthesis of DNA Duplexes Containing Reduced Acetaldehyde Interstrand Cross-Links.
J Am Chem Soc
; 145(2): 953-959, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36584283
4.
Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.
Mol Cell
; 47(1): 50-60, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22658721
5.
Bypass of Mutagenic O(6)-Carboxymethylguanine DNA Adducts by Human Y- and B-Family Polymerases.
Chem Res Toxicol
; 29(9): 1493-503, 2016 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27404553
6.
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations.
Nucleic Acids Res
; 41(10): 5524-32, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23580550
7.
The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase.
Nucleic Acids Res
; 41(5): 3047-55, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23335782
8.
Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-π interactions.
Proc Natl Acad Sci U S A
; 109(46): 18755-60, 2012 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23112169
9.
O6-carboxymethylguanine in DNA forms a sequence context-dependent wobble base-pair structure with thymine.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 6): 1669-79, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24914978
10.
Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism.
Chem Sci
; 15(7): 2509-2517, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38362406
11.
Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism.
Science
; 382(6670): eabp9201, 2023 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37917677
12.
Insights into the DNA stabilizing contributions of a bicyclic cytosine analogue: crystal structures of DNA duplexes containing 7,8-dihydropyrido [2,3-d]pyrimidin-2-one.
Nucleic Acids Res
; 38(19): 6737-45, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20554855
13.
Convenient and efficient syntheses of oligodeoxyribonucleotides containing O(6)-(carboxymethyl)guanine and O(6)-(4-oxo-4-(3-pyridyl)butyl)guanine.
Nucleosides Nucleotides Nucleic Acids
; 31(4): 328-38, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22444194
14.
Crystal structures of DNA duplexes stabilized by bicyclic-C residues.
Nucleic Acids Symp Ser (Oxf)
; (52): 127-8, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18776286