Detalhe da pesquisa
1.
Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells.
Proc Natl Acad Sci U S A
; 120(4): e2208176120, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36652477
2.
Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia.
Br J Haematol
; 204(1): 206-220, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37726227
3.
Phase 3 trial of gilteritinib plus azacitidine vs azacitidine for newly diagnosed FLT3mut+ AML ineligible for intensive chemotherapy.
Blood
; 140(17): 1845-1857, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35917453
4.
Sensitive tumour detection and classification using plasma cell-free DNA methylomes.
Nature
; 563(7732): 579-583, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30429608
5.
Loss of expression of both miR-15/16 loci in CML transition to blast crisis.
Proc Natl Acad Sci U S A
; 118(11)2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33836616
6.
Venous thromboembolism incidence associated with pegylated asparaginase (ASP) compared to the native L-ASP: A retrospective analysis with an ASP-based protocol in adult patients with acute lymphoblastic leukaemia.
Br J Haematol
; 201(4): 645-652, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36794878
7.
SmMIP-tools: a computational toolset for processing and analysis of single-molecule molecular inversion probes-derived data.
Bioinformatics
; 38(8): 2088-2095, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35150236
8.
CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy.
Blood
; 137(16): 2171-2181, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33270841
9.
Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production.
Blood
; 138(3): 234-245, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34292323
10.
Very long chain fatty acid metabolism is required in acute myeloid leukemia.
Blood
; 137(25): 3518-3532, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33720355
11.
CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.
Blood
; 137(5): 661-677, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33197925
12.
Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid ß-oxidation and inducing lipotoxicity.
Haematologica
; 108(9): 2343-2357, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37021547
13.
Tracing the origins of relapse in acute myeloid leukaemia to stem cells.
Nature
; 547(7661): 104-108, 2017 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28658204
14.
Combined loss of function of two different loci of miR-15/16 drives the pathogenesis of acute myeloid leukemia.
Proc Natl Acad Sci U S A
; 117(22): 12332-12340, 2020 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424097
15.
Mitochondrial carrier homolog 2 is necessary for AML survival.
Blood
; 136(1): 81-92, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32299104
16.
Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia.
Haematologica
; 107(11): 2548-2561, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199506
17.
Clinical significance of clonal hematopoiesis in the setting of autologous stem cell transplantation for lymphoma.
Am J Hematol
; 97(12): 1538-1547, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36087071
18.
A 17-gene stemness score for rapid determination of risk in acute leukaemia.
Nature
; 540(7633): 433-437, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27926740
19.
A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency.
Blood
; 133(20): 2198-2211, 2019 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30796022
20.
Measurable residual disease monitoring provides insufficient lead-time to prevent morphologic relapse in the majority of patients with core-binding factor acute myeloid leukemia.
Haematologica
; 106(1): 56-63, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31896684