Detalhe da pesquisa
1.
Generation of murine tumor models refractory to αPD-1/-L1 therapies due to defects in antigen processing/presentation or IFNγ signaling using CRISPR/Cas9.
PLoS One
; 19(3): e0287733, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427670
2.
Exploiting an Interleukin-15 Heterodimeric Agonist (N803) for Effective Immunotherapy of Solid Malignancies.
Cells
; 12(12)2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37371081
3.
Preclinical and clinical studies of a tumor targeting IL-12 immunocytokine.
Front Oncol
; 13: 1321318, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260854
4.
Tumor-targeted interleukin-12 synergizes with entinostat to overcome PD-1/PD-L1 blockade-resistant tumors harboring MHC-I and APM deficiencies.
J Immunother Cancer
; 10(6)2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764364
5.
Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa.
Oncoimmunology
; 10(1): 1915561, 2021 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33996267
6.
Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape.
Nat Commun
; 12(1): 5151, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34446712
7.
Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.
Nat Med
; 25(1): 141-151, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420753
8.
Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy.
J Immunother Cancer
; 5: 33, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28428882
9.
Immunoregulatory pathways following strong inflammatory processes markedly impair CD4+ T cell responses.
Hum Vaccin Immunother
; 12(9): 2249-52, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27409155