Detalhe da pesquisa
1.
The Dual Oxidase Duox2 stabilized with DuoxA2 in an enzymatic complex at the surface of the cell produces extracellular H2O2 able to induce DNA damage in an inducible cellular model.
Exp Cell Res
; 384(1): 111620, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31513783
2.
NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation.
Proc Natl Acad Sci U S A
; 112(16): 5051-6, 2015 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25848056
3.
The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.
Exp Cell Res
; 318(18): 2353-64, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22814254
4.
Severe Autoimmune Thyroiditis in Transgenic NOD.H2h4 Mice Expressing Interleukin-4 in the Thyroid.
Thyroid
; 33(3): 351-364, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36416242
5.
Murine Thyroid IL-4 Expression Worsens Hypothyroidism on Iodine Restriction and Mitigates Graves Disease Development.
Endocrinology
; 163(9)2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35881515
6.
Functional model of rat thyroid follicles cultured in Matrigel.
Endocr Connect
; 10(5): 570-578, 2021 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33909590
7.
Compound heterozygosity for a novel hemizygous missense mutation and a partial deletion affecting the catalytic core of the H2O2-generating enzyme DUOX2 associated with transient congenital hypothyroidism.
Hum Mutat
; 31(4): E1304-19, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20187165
8.
Dissecting the Role of Thyrotropin in the DNA Damage Response in Human Thyrocytes after 131I, γ Radiation and H2O2.
J Clin Endocrinol Metab
; 105(3)2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31701151
9.
DUOX Defects and Their Roles in Congenital Hypothyroidism.
Methods Mol Biol
; 1982: 667-693, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31172499
10.
Factors contributing to the resistance of the thyrocyte to hydrogen peroxide.
Mol Cell Endocrinol
; 481: 62-70, 2019 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30476559
11.
Expression, Localization, and Regulation of the Sodium Bicarbonate Cotransporter NBCe1 in the Thyroid.
Thyroid
; 29(2): 290-301, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30526387
12.
Gene expression in RET/PTC3 and E7 transgenic mouse thyroids: RET/PTC3 but not E7 tumors are partial and transient models of human papillary thyroid cancers.
Endocrinology
; 149(10): 5107-17, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18583418
13.
Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor.
Mol Endocrinol
; 21(6): 1408-21, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17374849
14.
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.
J Endocrinol
; 192(3): 615-26, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17332529
15.
Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.
Thyroid
; 26(10): 1499-1512, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27599561
16.
Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.
Antioxid Redox Signal
; 20(17): 2776-93, 2014 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24161126
17.
Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2.
Free Radic Biol Med
; 56: 216-25, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23010498
18.
IFNß/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response.
Cell Res
; 23(5): 673-90, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23545780
19.
Comparative analysis of the thyrocytes and T cells: responses to H2O2 and radiation reveals an H2O2-induced antioxidant transcriptional program in thyrocytes.
J Clin Endocrinol Metab
; 98(10): E1645-54, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23666977
20.
Stroma cell-derived factor-1α signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes.
PLoS One
; 8(2): e56007, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23460790