[Multiple applications of closed permanent wet dressings. Their mode of action]. / Las múltiples aplicaciones de las curas húmedas permanentes cerradas. Su mecanismo de acción.

New applications and forms of Darier's humid permanent closed cures are analysed specially in connection with concepts of cutaneous hydratation. The multiplicity of their application however makes it necessary to find an explanation for their excellent effects which are probably related to the anti-inflammatory, antipruritic and antiinfectious actions as well as the permanent draining effect from the deeper layers to the surface of the epidermis. The hydratation affected by HPCC is very important in dry and exudative stasis dermatitis with both a complete or a partial loss of stratum corneum. Cutaneous eutrophia is restored quite rapidly and an anti-infectious effect is brought about simultaneously. Especially in cases of stasis dermatitis with excessive secretions and pus formation the permanent drainage and hydratation make possible rapid healing. The preference for sodium borate does not exclude the use of other substance both alone or in combination. On the contrary, HPCC may be employed with especific antibiotics. Topical corticosteroid and antibiotic combination is frequently used in stasis dermatitis. In cases of pyoderma, the results obtained are definitively better when antibiotics are of the treatment. Eventually systematic corticoids may be included in the therapeutic arsenal.

[ORF. Epidemiological, histopathological and clinical considerations, apropos of a case]. / ORF. Consideraciones clínicas, histopathlógicas y epidemiológicas a propósito de un caso

The observation belongs to a 22 year-old man, who presented a lesion in the index finger of the right hand, with a nodular induration, which later turned into an ulcer and was cured in a month and a half. In the beginning it was painless, becoming painful after the third week. He was given a treatment of a simple topical application. The histopathologic study showed the existence of an inflammatory chronic process with epidermic alterations characterised by the presence of necrosis and vesicles (reticular degeneration). There was also a significant presence of mural necrosis of vessels of the papillar dermis and subpapillar plexus, with recent partial mural thrombosis, that authors consider of importance in the pathogenic of the process. Comments are made about the evolution of the illness in man and in caprines and ovines. On enclose the histopathologic study of a biopsy of lip, extracted from a sheep affected by this illness. This showed a microscopic picture similar to the one described above.

[Variable pseudoerythroplasic telangiectasis balanitis]. / Balanitis pseudoeritroplástica telangiectásica variable

This is a special case of balanitis, that authors separate from entities clinically established such as Erthroplasie of Queyrat, Balanitis of Zoon, Liquenoide Balantis with Plasmocytes and the Balantis of Sulsberger and Garbe's illness. The V. P. T. B. is clinically characterized by the presence of telangiectasies, ertroplasiform aspect, without any infiltration, non purpure, the V. P. T. B. goes through a first period truly esythematous and a second one in which these is also desquamation. That cycle is completed in a month. At the histopathologic level, the most important characteristics are: epidermis with its Malpighian layer in a normal state, the basal layers showing hidropic degeneration. The repper dermis shows a lichenoid picture that, in certain places affects the basal layer. The infiltrate is composed of: lymphocytes, monocytes and plasmocytes. Numerous telangiectasies are also observed.

[Epidermal peripilar nevus]. / Nevus epidérmico peripilar

A classic case of Epidermal Nevus with a particular peripilar arrangement is presented. Histopathologically, acanthosis, hyperkeratosis and papillomatosis is observed. The indemnity of the hair appendages was demonstrated in three biopsies. Some observations are made about the classification of the epidermal nevus following recent research which includes epidermolytic hyperkeratosis and linear includes epidermolytic hyperkatosis and linear inflammatory nevus. Follicular and comedo nevus, which was included in the differential diagnosis of this patient, is discussed.

[Furunculoid myiasis caused by Dermatobia hominis]. / Miásis forunculoide por "dermatobia hominis"

The authors report a case of forunculoid miasis by "Dermatobia hominis" ("Ura" fly). a process that being not very common in the Argentine Republic is sometimes misjudged as a furunculosis. The patient reported, a white woman, 51, travelled to a zone where this parasitose is endemid. After some time of her stay there, she noted three small nodes in her vulvar region. They grew on until reaching nearly the size of a walnut. At her first consultation with a gynecologist it was taken as a case of furuncolosis and treated with antibiotics. As the treatment didn't prove succesful, she asked for dermatological advice. It was then possible to verify the presence of three nodes. In the central hole of one of them, there could be seen a whitish body that soon disappeared inwards. This lead to the diagnosis of forunculoid miasis. An accurate and easy-to-perform treatment was carried out: a 1% solution of formaldehyde in distilled water was infused through the central hole of each node. This determined the larva's caudal extremity to appear in search of air. It was taken advantage of this situation to remove the larvae with a pair of nippers. "Dermatobia hominis" is widely spread in the warm-climated Argentine northern provinces of Chaco, Formosa and Misiones, as well as in Brazil, Paraguay and some regions of Uruguay. It is also known under the name of "Ura". It is a large fly, yellow faced, with dark-blue thorax; an almost rombic metallic-blue abdomen, orange antennae and legs, and dark-brown wings. It lives on the nutrients spared during its larval stage and both fecundation and oviposition, take place along its week-long life. The fecundated female catches different haematophagus insects on the wing, sticking sets of eggs to their abdomens. An embryo developes in each egg, being ready to emerge in a week but does this only when the bearer insect settles on a homeothermal being piercing and penetrating the skin of the new guest in about 10 minutes.

[Folliculitis and abscessed nodular perifolliculitis of the upper limb caused by Trichophyton mentagrophytes, presumably corticoid-related]. / Foliculitis y perifoliculitis nodular abscedada de miembro superior por Trichophyton mentagrophytes, presumiblemente cortisónica.

The authors present a follicolitis and perifolliculitis case with abscess and profound nodules, unfolded on a patient who had been subjected to an abusive local an general treatment with corticoids. That process had progressed with similar characteristics to Majocchi's tricophytic granuloma, although this case appeared over the application of that therapeutic. The allergological study could prove a depression of the cellular immunity, but at the same time it demonstrated an abnormal reaction, as an anaphylactoid one, at trychophytin and penicillin.

[Early or malignant ulcerative syphilis. Considerations apropos of 2 cases. Bibliographic analysis]. / Lúes ulcerativa precoz o maligna. Consideraciones a propósito de dos casos. Análisis bibliográfico.

Two cases of early ulcerative syphilis observed in the city of La Plata, Argentina, in the last 13 years are presented. Cases n.o 1, classified as Queyrat type, was in a previously bad general condition, due both to excessive smoking and alcoholism and showed a classic blood serologic test, that was slightly reactive. Case n.o 2, Milian type, presented a previously excellent general condition. The classic blood serologic test and FTAabs. were strongly reactive. It showed only a significant depression of cell immunity, with regard to the bacterial cutaneous proofs (bacterial skin-tests) carried out "in vivo". In both cases the clinical aspect was similar, with ulcerative necrotic lesions and affectation of the general condition which coincided with the outbreak of those lesions. The response to treatment was good, with rapid improvement of the general condition while the improvement of the skin lesions was slower and occurred only within 3 weeks.

[Topical use of the new corticoid difluocortolone valerate in dermatology]. / Zur topischen Anwendung des neuen Kortikoids Diflucortolonvalerianat in der Dermatologie

The object of the present study was to investigate the clinical efficacy of Nerisona Fatty Ointment in very dry skin conditions. A total of 37 patients, most of them with chronic dermatoses, was treated. Either very good or good results were achieved in 83.8% of the cases. The side effects observed were very slight.

Nevo nevocelular compuesto de desarrollo agudo (variedad: extensivo superficial). / Compound nevocellular nevus of acute course (variety: superficial extensive)

Se presenta un caso de nevo nevocelular piloso de desarrollo agudo, con tendencia al gigantismo, desarrollado en menos de 4 meses. Iniciado a los 20 dias de edad adquirio caracteres inusitados en el breve lapso mencionado. En el curso de la presentacion se hacen consideraciones sobre las tumoraciones de desarrollo agudo entre las que se incluye ahora, en la experiencia de los autores, este nevo nevocelular pigmentado y piloso. En la histopatologia es de destacar la profundidad observada en la zona central y mas saliente de la lesion, que lo muestran llegando hasta la hipodermis y la actividad juncional en los bordes de la lesion.Este hecho nos ha llevado a asimilarlo en su parecido extensivo al melanoma maligno superficial de igual nombre. Terminan haciendose consideraciones sobre la necesidad del tratamiento radical rapido, dentro de lo posible, asimilando esta terapeutica a la practicada en casos de nevos pigmentarios gigantes pilosos congenitos

Nevo nevocelular compuesto de desarrollo agudo (variedad: extensivo superficial). / Compound nevocellular nevus of acute course (variety: superficial extensive)

Se presenta un caso de nevo nevocelular piloso de desarrollo agudo, con tendencia al gigantismo, desarrollado en menos de 4 meses. Iniciado a los 20 dias de edad adquirio caracteres inusitados en el breve lapso mencionado. En el curso de la presentacion se hacen consideraciones sobre las tumoraciones de desarrollo agudo entre las que se incluye ahora, en la experiencia de los autores, este nevo nevocelular pigmentado y piloso. En la histopatologia es de destacar la profundidad observada en la zona central y mas saliente de la lesion, que lo muestran llegando hasta la hipodermis y la actividad juncional en los bordes de la lesion.Este hecho nos ha llevado a asimilarlo en su parecido extensivo al melanoma maligno superficial de igual nombre. Terminan haciendose consideraciones sobre la necesidad del tratamiento radical rapido, dentro de lo posible, asimilando esta terapeutica a la practicada en casos de nevos pigmentarios gigantes pilosos congenitos

Necrosis grasa profusa del recien nacido. / Diffuse fat necrosis of the newborn infant

Es presentado un caso de necrosis grasa del recien nacido, de desarrollo profuso, dando origen en el dorso a una gran tumoracion. Se destacan en el curso del trabajo las dificultades diagnosticas a que pueden dar lugar las circunstancias etiologicas y la evolucion con restitucion integral, o bien con secuelas

Dermatofibromas multiples, con histologia en un elemento de tipo histiocitofibroma seudosarcomatoso. / Multiple cutaneous fibromas, with histology in an element type seudosarcomatous histiocytofibroma

Se comunica la presentacion en el mismo enfermo de 5 lesiones fibromatosas cutaneas, aparecidas en el lapso de 1 ano. Cuatro de ellas mostraron histologia de dermatofibromas ricos en fibroblastos y colageno. El quinto elemento estaba constituido por un predominio de formas celulares histiociticas con imagenes que simulan la "rueda de carro" y con aumento del indice mitotico tipico (histiocitofibroma dermico seudosarcomatoso). En el curso del trabajo son analizadas tambien las formaciones seudosarcomatosas con las cuales debe realizarse el diagnostico diferencial

Papiloma venereo perianal a forma clinica cronica tumoral. / Tumoral chronic clinical form of perianal venereal papilloma

Una forma muy especial del papiloma venereo es descripta, asignandole el nombre de papiloma venereo a forma tumoral cronica. Se realiza asimismo su ubicacion dentro de todas las formas conocidas de papihaber precedido al epitelioma/

Epitelioma espinocelular de pene versus papiloma venereo. / Spinocellular epithelioma of the penis us venereal papilloma

Se presenta un caso de tumor del glande en el que se constata histologicamente epitelioma espinocelular, junto a un papiloma venereo de tipo comun, desarollado en su vecindad. Clinicamente el papiloma parece haber precedido al epitelioma.

Papiloma venereo perianal a forma clinica cronica tumoral. / Tumoral chronic clinical form of perianal venereal papilloma

Una forma muy especial del papiloma venereo es descripta, asignandole el nombre de papiloma venereo a forma tumoral cronica. Se realiza asimismo su ubicacion dentro de todas las formas conocidas de papihaber precedido al epitelioma/

Epitelioma espinocelular de pene versus papiloma venereo. / Spinocellular epithelioma of the penis us venereal papilloma

Se presenta un caso de tumor del glande en el que se constata histologicamente epitelioma espinocelular, junto a un papiloma venereo de tipo comun, desarollado en su vecindad. Clinicamente el papiloma parece haber precedido al epitelioma.

Necrosis grasa profusa del recien nacido. / Diffuse fat necrosis of the newborn infant

Es presentado un caso de necrosis grasa del recien nacido, de desarrollo profuso, dando origen en el dorso a una gran tumoracion. Se destacan en el curso del trabajo las dificultades diagnosticas a que pueden dar lugar las circunstancias etiologicas y la evolucion con restitucion integral, o bien con secuelas

Dermatofibromas multiples, con histologia en un elemento de tipo histiocitofibroma seudosarcomatoso. / Multiple cutaneous fibromas, with histology in an element type seudosarcomatous histiocytofibroma

Se comunica la presentacion en el mismo enfermo de 5 lesiones fibromatosas cutaneas, aparecidas en el lapso de 1 ano. Cuatro de ellas mostraron histologia de dermatofibromas ricos en fibroblastos y colageno. El quinto elemento estaba constituido por un predominio de formas celulares histiociticas con imagenes que simulan la "rueda de carro" y con aumento del indice mitotico tipico (histiocitofibroma dermico seudosarcomatoso). En el curso del trabajo son analizadas tambien las formaciones seudosarcomatosas con las cuales debe realizarse el diagnostico diferencial