Detalhe da pesquisa
1.
Isoform-Specific Biased Agonism of Histamine H3 Receptor Agonists.
Mol Pharmacol
; 91(2): 87-99, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864425
2.
Upregulation of neurotrophins by S 47445, a novel positive allosteric modulator of AMPA receptors in aged rats.
Pharmacol Res
; 121: 59-69, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28442348
3.
The effects of antidepressant treatment in prenatally stressed rats support the glutamatergic hypothesis of stress-related disorders.
J Neurosci
; 34(6): 2015-24, 2014 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24501344
4.
Evaluation of the effects of therapeutic and supratherapeutic doses of agomelatine on the QT/QTc interval: a phase I, randomized, double-blind, placebo-controlled and positive-controlled, crossover thorough QT/QTc study conducted in healthy volunteers.
J Cardiovasc Pharmacol
; 64(5): 440-51, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24977347
5.
Chronic treatment with agomelatine or venlafaxine reduces depolarization-evoked glutamate release from hippocampal synaptosomes.
BMC Neurosci
; 14: 75, 2013 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23895555
6.
Chronic agomelatine treatment corrects the abnormalities in the circadian rhythm of motor activity and sleep/wake cycle induced by prenatal restraint stress in adult rats.
Int J Neuropsychopharmacol
; 16(2): 323-38, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22310059
7.
Pharmacological or genetic blockade of the dopamine D3 receptor increases cell proliferation in the hippocampus of adult mice.
J Neurochem
; 123(5): 811-23, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22957735
8.
Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety.
Int J Neuropsychopharmacol
; 15(3): 321-35, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21473810
9.
Chronic stress and antidepressant agomelatine induce region-specific changes in synapsin I expression in the rat brain.
J Neurosci Res
; 89(10): 1646-57, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21688292
10.
Absence of psychostimulant effects of a supratherapeutic dose of tianeptine: a placebo-controlled study versus methylphenidate in young healthy volunteers.
J Clin Psychopharmacol
; 31(4): 441-8, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21694627
11.
Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways.
BMC Neurosci
; 11: 68, 2010 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-20525261
12.
Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice.
Int J Neuropsychopharmacol
; 13(6): 759-74, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19775499
13.
The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures.
Int J Neuropsychopharmacol
; 13(8): 1035-51, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20663270
14.
The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats.
Int J Neuropsychopharmacol
; 12(3): 329-41, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18706130
15.
S 47445 counteracts the behavioral manifestations and hippocampal neuroplasticity changes in bulbectomized mice.
Prog Neuropsychopharmacol Biol Psychiatry
; 93: 205-213, 2019 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30980840
16.
Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 receptor antagonists.
Neuropharmacology
; 144: 244-255, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30359639
17.
S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiological and behavioral characterization in vivo.
J Pharmacol Exp Ther
; 324(2): 600-11, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18024787
18.
Markers of D(2) and D(3) receptor activity in vivo: PET scan and prolactin.
Therapie
; 63(3): 237-42, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18718212
19.
α2- and ß2-Adrenoreceptor-Mediated Efficacy of the Atypical Antidepressant Agomelatine Combined With Gabapentin to Suppress Allodynia in Neuropathic Rats With Ligated Infraorbital or Sciatic Nerve.
Front Pharmacol
; 9: 587, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29930510
20.
First evidence of melatonin receptors distribution in the suprachiasmatic nucleus of tree shrew brain.
Neuro Endocrinol Lett
; 28(3): 267-73, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17627260