Detalhe da pesquisa
1.
Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson's disease models.
Hum Mol Genet
; 32(18): 2808-2821, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37384414
2.
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice.
Nat Chem Biol
; 16(6): 667-675, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393901
3.
Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization.
J Am Chem Soc
; 137(14): 4771-7, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25785540
4.
Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities.
Prog Lipid Res
; 89: 101194, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150527
5.
Fluorescence-Based NAPE-PLD Activity Assay.
Methods Mol Biol
; 2576: 233-240, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152191
6.
Structure-Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of N-Acylphosphatidylethanolamine Phospholipase D.
J Med Chem
; 64(1): 481-515, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33382264
7.
Structure-Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family.
J Med Chem
; 63(17): 9340-9359, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787138
8.
Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI.
ACS Chem Biol
; 14(2): 164-169, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30620559
9.
Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.
Science
; 356(6342): 1084-1087, 2017 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28596366
10.
Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.
Nat Commun
; 8: 13958, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28045021
11.
Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib.
Chem Commun (Camb)
; 52(21): 4064-7, 2016 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26894389
12.
Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites.
J Med Chem
; 56(3): 1262-75, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23320547