Detalhe da pesquisa
1.
An Overview of Next-Generation Androgen Receptor-Targeted Therapeutics in Development for the Treatment of Prostate Cancer.
Int J Mol Sci
; 22(4)2021 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33672769
2.
Role and pharmacologic significance of cytochrome P-450 2D6 in oxidative metabolism of toremifene and tamoxifen.
Int J Cancer
; 132(6): 1475-85, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22915089
3.
Metabolism-Guided Selective Androgen Receptor Antagonists: Design, Synthesis, and Biological Evaluation for Activity against Enzalutamide-Resistant Prostate Cancer.
J Med Chem
; 66(5): 3372-3392, 2023 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36825758
4.
Exploration and Biological Evaluation of Basic Heteromonocyclic Propanamide Derivatives as SARDs for the Treatment of Enzalutamide-Resistant Prostate Cancer.
J Med Chem
; 64(15): 11045-11062, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34269581
5.
Pyrazol-1-yl-propanamides as SARD and Pan-Antagonists for the Treatment of Enzalutamide-Resistant Prostate Cancer.
J Med Chem
; 63(21): 12642-12665, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33095584
6.
Recent and emerging anti-diabetes targets.
Med Res Rev
; 29(1): 125-95, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18855890
7.
New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity.
J Med Chem
; 62(2): 491-511, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525603
8.
Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators.
Bioorg Med Chem Lett
; 18(20): 5567-70, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18805694
9.
Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.
J Med Chem
; 49(19): 5845-8, 2006 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16970409
10.
Synthesis of oxazolidinedione derived bicalutamide analogs.
Tetrahedron Lett
; 47(23): 3953-3955, 2006 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18079987
11.
Cesium fluoride and tetra-n-butylammonium fluoride mediated 1,4-N-->O shift of disubstituted phenyl ring of a bicalutamide derivative.
Tetrahedron Lett
; 47(23): 3941-3944, 2006 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18079983
12.
Synthesis of irreversibly binding bicalutamide analogs for imaging studies.
Tetrahedron Lett
; 46(28): 4821-4823, 2005 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18079986
13.
A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor.
J Med Chem
; 47(15): 3765-76, 2004 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15239655
14.
Synthesis of 1-boraadamantaneamine derivatives with selective astrocyte vs C6 glioma antiproliferative activity. A novel class of anti-hepatitis C agents with potential to bind CD81.
J Med Chem
; 46(14): 2823-33, 2003 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-12825926
15.
Selective androgen receptor modulators for the prevention and treatment of muscle wasting associated with cancer.
Curr Opin Support Palliat Care
; 7(4): 345-51, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24189892
16.
Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation.
PLoS One
; 8(12): e83380, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24386191
17.
Androgen receptor antagonists: a patent review (2008-2011).
Expert Opin Ther Pat
; 22(5): 541-65, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22583332
18.
Design, synthesis, and SAR studies of 4-substituted methoxylbenzoyl-aryl-thiazoles analogues as potent and orally bioavailable anticancer agents.
J Med Chem
; 54(13): 4678-93, 2011 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21557538
19.
Estrogen receptor beta selective nonsteroidal estrogens: seeking clinical indications.
Expert Opin Ther Pat
; 20(4): 507-34, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20302450
20.
Selective androgen receptor modulators in preclinical and clinical development.
Nucl Recept Signal
; 6: e010, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-19079612