Detalhe da pesquisa
1.
Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits.
Am J Hum Genet
; 109(1): 66-80, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995504
2.
Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.
Am J Hum Genet
; 109(10): 1727-1741, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055244
3.
Mediation analysis of multiple mediators with incomplete omics data.
Genet Epidemiol
; 47(1): 61-77, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36125445
4.
Genetic effects on liver chromatin accessibility identify disease regulatory variants.
Am J Hum Genet
; 108(7): 1169-1189, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34038741
5.
Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits.
Genome Res
; 31(12): 2258-2275, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34815310
6.
Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci.
PLoS Genet
; 17(10): e1009865, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699533
7.
Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts.
Am J Hum Genet
; 106(1): 112-120, 2020 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31883642
8.
The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance.
PLoS Genet
; 16(9): e1009018, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32925908
9.
Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences.
PLoS Genet
; 16(9): e1009019, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32915782
10.
Integration of DNA sequencing with population pharmacokinetics to improve the prediction of irinotecan exposure in cancer patients.
Br J Cancer
; 126(4): 640-651, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34703007
11.
Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits.
Am J Hum Genet
; 105(4): 773-787, 2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564431
12.
ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.
Int J Obes (Lond)
; 46(8): 1478-1486, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35589964
13.
Otitis media susceptibility and shifts in the head and neck microbiome due to SPINK5 variants.
J Med Genet
; 58(7): 442-452, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32709676
14.
Assessing exposure effects on gene expression.
Genet Epidemiol
; 44(6): 601-610, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511796
15.
Enhancer deletion and allelic effects define a regulatory molecular mechanism at the VLDLR cholesterol GWAS locus.
Hum Mol Genet
; 28(6): 888-895, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30445632
16.
Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution.
Hum Mol Genet
; 28(24): 4161-4172, 2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31691812
17.
Deciphering the Emerging Complexities of Molecular Mechanisms at GWAS Loci.
Am J Hum Genet
; 103(5): 637-653, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388398
18.
Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits.
Am J Hum Genet
; 103(4): 535-552, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30290150
19.
A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.
Am J Hum Genet
; 102(4): 620-635, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29625024
20.
Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.
PLoS Genet
; 14(4): e1007275, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29621232