Detalhe da pesquisa
1.
Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy.
Biochem Soc Trans
; 50(3): 1105-1118, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35587168
2.
Neutrophil Degranulation, Plasticity, and Cancer Metastasis.
Trends Immunol
; 40(3): 228-242, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30777721
3.
Upregulated expression and function of the α4ß1 integrin in multiple myeloma cells resistant to bortezomib.
J Pathol
; 252(1): 29-40, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32501543
4.
New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure-activity relationships, and molecular modelling.
J Enzyme Inhib Med Chem
; 36(1): 2025-2044, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34514909
5.
Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy: Thematic Review Series: Biology of Lipid Rafts.
J Lipid Res
; 61(5): 611-635, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33715811
6.
Potent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring.
Bioorg Chem
; 98: 103755, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32200330
7.
Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active component.
Mol Carcinog
; 57(3): 347-360, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29073716
8.
Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling.
Chemistry
; 23(7): 1676-1685, 2017 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27885731
9.
C-Geranylated flavonoids from Paulownia tomentosa fruits with antimicrobial potential and synergistic activity with antibiotics.
Pharm Biol
; 54(8): 1398-407, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26789098
10.
Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.
Apoptosis
; 20(5): 584-606, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25702154
11.
ERK1/2 acts as a switch between necrotic and apoptotic cell death in ether phospholipid edelfosine-treated glioblastoma cells.
Pharmacol Res
; 95-96: 2-11, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25749008
12.
Synthesis of Bioconjugate Sesterterpenoids with Phospholipids and Polyunsaturated Fatty Acids.
Molecules
; 21(1): E47, 2015 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26729084
13.
Alteration of plasma membrane organization by an anticancer lysophosphatidylcholine analogue induces intracellular acidification and internalization of plasma membrane transporters in yeast.
J Biol Chem
; 288(12): 8419-8432, 2013 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23344949
14.
Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast.
J Biol Chem
; 288(12): 8405-8418, 2013 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23335509
15.
Suppression of metastatic organ colonization and antiangiogenic activity of the orally bioavailable lipid raft-targeted alkylphospholipid edelfosine.
Biomed Pharmacother
; 171: 116149, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266621
16.
Synthesis and evaluation as antitumor agents of 1,4-naphthohydroquinone derivatives conjugated with amino acids and purines.
Arch Pharm (Weinheim)
; 346(12): 882-90, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24123148
17.
Antitumor activity of alkylphospholipid edelfosine in prostate cancer models and endoplasmic reticulum targeting.
Biomed Pharmacother
; 167: 115436, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37683591
18.
The metalloprotease ADAM8 is associated with and regulates the function of the adhesion receptor PSGL-1 through ERM proteins.
Eur J Immunol
; 41(12): 3436-42, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22229154
19.
Raft platforms highly enriched in cholesterol: major scaffolds for IL-6 signalling assembly with implications in inflammation and cancer.
FEBS J
; 289(19): 5891-5894, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35727702
20.
Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer.
Eur J Med Chem
; 239: 114504, 2022 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35724566