Pesquisa | Biblioteca Virtual em Saúde

1.

Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques.

Saunders, Kevin O; Counts, James; Thakur, Bhishem; Stalls, Victoria; Edwards, Robert; Manne, Kartik; Lu, Xiaozhi; Mansouri, Katayoun; Chen, Yue; Parks, Rob; Barr, Maggie; Sutherland, Laura; Bal, Joena; Havill, Nicholas; Chen, Haiyan; Machiele, Emily; Jamieson, Nolan; Hora, Bhavna; Kopp, Megan; Janowska, Katarzyna; Anasti, Kara; Jiang, Chuancang; Van Itallie, Elizabeth; Venkatayogi, Sravani; Eaton, Amanda; Henderson, Rory; Barbosa, Christopher; Alam, S Munir; Santra, Sampa; Weissman, Drew; Moody, M Anthony; Cain, Derek W; Tam, Ying K; Lewis, Mark; Williams, Wilton B; Wiehe, Kevin; Montefiori, David C; Acharya, Priyamvada; Haynes, Barton F.

Cell ; 187(1): 79-94.e24, 2024 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-38181743

2.

Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.

Williams, Wilton B; Alam, S Munir; Ofek, Gilad; Erdmann, Nathaniel; Montefiori, David C; Seaman, Michael S; Wagh, Kshitij; Korber, Bette; Edwards, Robert J; Mansouri, Katayoun; Eaton, Amanda; Cain, Derek W; Martin, Mitchell; Hwang, JongIn; Arus-Altuz, Aria; Lu, Xiaozhi; Cai, Fangping; Jamieson, Nolan; Parks, Robert; Barr, Maggie; Foulger, Andrew; Anasti, Kara; Patel, Parth; Sammour, Salam; Parsons, Ruth J; Huang, Xiao; Lindenberger, Jared; Fetics, Susan; Janowska, Katarzyna; Niyongabo, Aurelie; Janus, Benjamin M; Astavans, Anagh; Fox, Christopher B; Mohanty, Ipsita; Evangelous, Tyler; Chen, Yue; Berry, Madison; Kirshner, Helene; Van Itallie, Elizabeth; Saunders, Kevin O; Wiehe, Kevin; Cohen, Kristen W; McElrath, M Juliana; Corey, Lawrence; Acharya, Priyamvada; Walsh, Stephen R; Baden, Lindsey R; Haynes, Barton F.

Cell ; 2024 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-38761800

3.

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.

Williams, Wilton B; Meyerhoff, R Ryan; Edwards, R J; Li, Hui; Manne, Kartik; Nicely, Nathan I; Henderson, Rory; Zhou, Ye; Janowska, Katarzyna; Mansouri, Katayoun; Gobeil, Sophie; Evangelous, Tyler; Hora, Bhavna; Berry, Madison; Abuahmad, A Yousef; Sprenz, Jordan; Deyton, Margaret; Stalls, Victoria; Kopp, Megan; Hsu, Allen L; Borgnia, Mario J; Stewart-Jones, Guillaume B E; Lee, Matthew S; Bronkema, Naomi; Moody, M Anthony; Wiehe, Kevin; Bradley, Todd; Alam, S Munir; Parks, Robert J; Foulger, Andrew; Oguin, Thomas; Sempowski, Gregory D; Bonsignori, Mattia; LaBranche, Celia C; Montefiori, David C; Seaman, Michael; Santra, Sampa; Perfect, John; Francica, Joseph R; Lynn, Geoffrey M; Aussedat, Baptiste; Walkowicz, William E; Laga, Richard; Kelsoe, Garnett; Saunders, Kevin O; Fera, Daniela; Kwong, Peter D; Seder, Robert A; Bartesaghi, Alberto; Shaw, George M.

Cell ; 184(11): 2955-2972.e25, 2021 05 27.

Artigo em Inglês | MEDLINE | ID: mdl-34019795

4.

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus.

Korber, Bette; Fischer, Will M; Gnanakaran, Sandrasegaram; Yoon, Hyejin; Theiler, James; Abfalterer, Werner; Hengartner, Nick; Giorgi, Elena E; Bhattacharya, Tanmoy; Foley, Brian; Hastie, Kathryn M; Parker, Matthew D; Partridge, David G; Evans, Cariad M; Freeman, Timothy M; de Silva, Thushan I; McDanal, Charlene; Perez, Lautaro G; Tang, Haili; Moon-Walker, Alex; Whelan, Sean P; LaBranche, Celia C; Saphire, Erica O; Montefiori, David C.

Cell ; 182(4): 812-827.e19, 2020 08 20.

Artigo em Inglês | MEDLINE | ID: mdl-32697968

5.

The role of antibodies in HIV vaccines.

Mascola, John R; Montefiori, David C.

Annu Rev Immunol ; 28: 413-44, 2010.

Artigo em Inglês | MEDLINE | ID: mdl-20192810

6.

Bispecific Antibodies Against HIV.

Montefiori, David C.

Cell ; 165(7): 1563-1564, 2016 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-27315470

7.

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.

Bonsignori, Mattia; Zhou, Tongqing; Sheng, Zizhang; Chen, Lei; Gao, Feng; Joyce, M Gordon; Ozorowski, Gabriel; Chuang, Gwo-Yu; Schramm, Chaim A; Wiehe, Kevin; Alam, S Munir; Bradley, Todd; Gladden, Morgan A; Hwang, Kwan-Ki; Iyengar, Sheelah; Kumar, Amit; Lu, Xiaozhi; Luo, Kan; Mangiapani, Michael C; Parks, Robert J; Song, Hongshuo; Acharya, Priyamvada; Bailer, Robert T; Cao, Allen; Druz, Aliaksandr; Georgiev, Ivelin S; Kwon, Young D; Louder, Mark K; Zhang, Baoshan; Zheng, Anqi; Hill, Brenna J; Kong, Rui; Soto, Cinque; Mullikin, James C; Douek, Daniel C; Montefiori, David C; Moody, Michael A; Shaw, George M; Hahn, Beatrice H; Kelsoe, Garnett; Hraber, Peter T; Korber, Bette T; Boyd, Scott D; Fire, Andrew Z; Kepler, Thomas B; Shapiro, Lawrence; Ward, Andrew B; Mascola, John R; Liao, Hua-Xin; Kwong, Peter D.

Cell ; 165(2): 449-63, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-26949186

8.

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.

de Taeye, Steven W; Ozorowski, Gabriel; Torrents de la Peña, Alba; Guttman, Miklos; Julien, Jean-Philippe; van den Kerkhof, Tom L G M; Burger, Judith A; Pritchard, Laura K; Pugach, Pavel; Yasmeen, Anila; Crampton, Jordan; Hu, Joyce; Bontjer, Ilja; Torres, Jonathan L; Arendt, Heather; DeStefano, Joanne; Koff, Wayne C; Schuitemaker, Hanneke; Eggink, Dirk; Berkhout, Ben; Dean, Hansi; LaBranche, Celia; Crotty, Shane; Crispin, Max; Montefiori, David C; Klasse, P J; Lee, Kelly K; Moore, John P; Wilson, Ian A; Ward, Andrew B; Sanders, Rogier W.

Cell ; 163(7): 1702-15, 2015 Dec 17.

Artigo em Inglês | MEDLINE | ID: mdl-26687358

9.

Structural diversity of the SARS-CoV-2 Omicron spike.

Gobeil, Sophie M-C; Henderson, Rory; Stalls, Victoria; Janowska, Katarzyna; Huang, Xiao; May, Aaron; Speakman, Micah; Beaudoin, Esther; Manne, Kartik; Li, Dapeng; Parks, Rob; Barr, Maggie; Deyton, Margaret; Martin, Mitchell; Mansouri, Katayoun; Edwards, Robert J; Eaton, Amanda; Montefiori, David C; Sempowski, Gregory D; Saunders, Kevin O; Wiehe, Kevin; Williams, Wilton; Korber, Bette; Haynes, Barton F; Acharya, Priyamvada.

Mol Cell ; 82(11): 2050-2068.e6, 2022 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-35447081

10.

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies.

Gao, Feng; Bonsignori, Mattia; Liao, Hua-Xin; Kumar, Amit; Xia, Shi-Mao; Lu, Xiaozhi; Cai, Fangping; Hwang, Kwan-Ki; Song, Hongshuo; Zhou, Tongqing; Lynch, Rebecca M; Alam, S Munir; Moody, M Anthony; Ferrari, Guido; Berrong, Mark; Kelsoe, Garnett; Shaw, George M; Hahn, Beatrice H; Montefiori, David C; Kamanga, Gift; Cohen, Myron S; Hraber, Peter; Kwong, Peter D; Korber, Bette T; Mascola, John R; Kepler, Thomas B; Haynes, Barton F.

Cell ; 158(3): 481-91, 2014 Jul 31.

Artigo em Inglês | MEDLINE | ID: mdl-25065977

11.

Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.

Gorman, Jason; Mason, Rosemarie D; Nettey, Leonard; Cavett, Nicole; Chuang, Gwo-Yu; Peng, Dongjun; Tsybovsky, Yaroslav; Verardi, Raffaello; Nguyen, Richard; Ambrozak, David; Biris, Kristin; LaBranche, Celia C; Ramesh, Akshaya; Schramm, Chaim A; Zhou, Jing; Bailer, Robert T; Kepler, Thomas B; Montefiori, David C; Shapiro, Lawrence; Douek, Daniel C; Mascola, John R; Roederer, Mario; Kwong, Peter D.

Immunity ; 51(4): 724-734.e4, 2019 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-31586542

12.

Long-primed germinal centres with enduring affinity maturation and clonal migration.

Lee, Jeong Hyun; Sutton, Henry J; Cottrell, Christopher A; Phung, Ivy; Ozorowski, Gabriel; Sewall, Leigh M; Nedellec, Rebecca; Nakao, Catherine; Silva, Murillo; Richey, Sara T; Torres, Jonathan L; Lee, Wen-Hsin; Georgeson, Erik; Kubitz, Michael; Hodges, Sam; Mullen, Tina-Marie; Adachi, Yumiko; Cirelli, Kimberly M; Kaur, Amitinder; Allers, Carolina; Fahlberg, Marissa; Grasperge, Brooke F; Dufour, Jason P; Schiro, Faith; Aye, Pyone P; Kalyuzhniy, Oleksandr; Liguori, Alessia; Carnathan, Diane G; Silvestri, Guido; Shen, Xiaoying; Montefiori, David C; Veazey, Ronald S; Ward, Andrew B; Hangartner, Lars; Burton, Dennis R; Irvine, Darrell J; Schief, William R; Crotty, Shane.

Nature ; 609(7929): 998-1004, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36131022

13.

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.

Bonsignori, Mattia; Scott, Eric; Wiehe, Kevin; Easterhoff, David; Alam, S Munir; Hwang, Kwan-Ki; Cooper, Melissa; Xia, Shi-Mao; Zhang, Ruijun; Montefiori, David C; Henderson, Rory; Nie, Xiaoyan; Kelsoe, Garnett; Moody, M Anthony; Chen, Xuejun; Joyce, M Gordon; Kwong, Peter D; Connors, Mark; Mascola, John R; McGuire, Andrew T; Stamatatos, Leonidas; Medina-Ramírez, Max; Sanders, Rogier W; Saunders, Kevin O; Kepler, Thomas B; Haynes, Barton F.

Immunity ; 49(6): 1162-1174.e8, 2018 12 18.

Artigo em Inglês | MEDLINE | ID: mdl-30552024

14.

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses.

Saunders, Kevin O; Lee, Esther; Parks, Robert; Martinez, David R; Li, Dapeng; Chen, Haiyan; Edwards, Robert J; Gobeil, Sophie; Barr, Maggie; Mansouri, Katayoun; Alam, S Munir; Sutherland, Laura L; Cai, Fangping; Sanzone, Aja M; Berry, Madison; Manne, Kartik; Bock, Kevin W; Minai, Mahnaz; Nagata, Bianca M; Kapingidza, Anyway B; Azoitei, Mihai; Tse, Longping V; Scobey, Trevor D; Spreng, Rachel L; Rountree, R Wes; DeMarco, C Todd; Denny, Thomas N; Woods, Christopher W; Petzold, Elizabeth W; Tang, Juanjie; Oguin, Thomas H; Sempowski, Gregory D; Gagne, Matthew; Douek, Daniel C; Tomai, Mark A; Fox, Christopher B; Seder, Robert; Wiehe, Kevin; Weissman, Drew; Pardi, Norbert; Golding, Hana; Khurana, Surender; Acharya, Priyamvada; Andersen, Hanne; Lewis, Mark G; Moore, Ian N; Montefiori, David C; Baric, Ralph S; Haynes, Barton F.

Nature ; 594(7864): 553-559, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33971664

15.

Stabilized trimeric peptide immunogens of the complete HIV-1 gp41 N-heptad repeat and their use as HIV-1 vaccine candidates.

Wu, Chengwei; Raheem, Izzat T; Nahas, Debbie D; Citron, Michael; Kim, Peter S; Montefiori, David C; Ottinger, Elizabeth A; Hepler, Robert W; Hrin, Renee; Patel, Sangita B; Soisson, Stephen M; Joyce, Joseph G.

Proc Natl Acad Sci U S A ; 121(22): e2317230121, 2024 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-38768344

16.

Prevention efficacy of the broadly neutralizing antibody VRC01 depends on HIV-1 envelope sequence features.

Juraska, Michal; Bai, Hongjun; deCamp, Allan C; Magaret, Craig A; Li, Li; Gillespie, Kevin; Carpp, Lindsay N; Giorgi, Elena E; Ludwig, James; Molitor, Cindy; Hudson, Aaron; Williamson, Brian D; Espy, Nicole; Simpkins, Brian; Rudnicki, Erika; Shao, Danica; Rossenkhan, Raabya; Edlefsen, Paul T; Westfall, Dylan H; Deng, Wenjie; Chen, Lennie; Zhao, Hong; Bhattacharya, Tanmoy; Pankow, Alec; Murrell, Ben; Yssel, Anna; Matten, David; York, Talita; Beaume, Nicolas; Gwashu-Nyangiwe, Asanda; Ndabambi, Nonkululeko; Thebus, Ruwayhida; Karuna, Shelly T; Morris, Lynn; Montefiori, David C; Hural, John A; Cohen, Myron S; Corey, Lawrence; Rolland, Morgane; Gilbert, Peter B; Williamson, Carolyn; Mullins, James I.

Proc Natl Acad Sci U S A ; 121(4): e2308942121, 2024 Jan 23.

Artigo em Inglês | MEDLINE | ID: mdl-38241441

17.

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.

Pauthner, Matthias; Havenar-Daughton, Colin; Sok, Devin; Nkolola, Joseph P; Bastidas, Raiza; Boopathy, Archana V; Carnathan, Diane G; Chandrashekar, Abishek; Cirelli, Kimberly M; Cottrell, Christopher A; Eroshkin, Alexey M; Guenaga, Javier; Kaushik, Kirti; Kulp, Daniel W; Liu, Jinyan; McCoy, Laura E; Oom, Aaron L; Ozorowski, Gabriel; Post, Kai W; Sharma, Shailendra K; Steichen, Jon M; de Taeye, Steven W; Tokatlian, Talar; Torrents de la Peña, Alba; Butera, Salvatore T; LaBranche, Celia C; Montefiori, David C; Silvestri, Guido; Wilson, Ian A; Irvine, Darrell J; Sanders, Rogier W; Schief, William R; Ward, Andrew B; Wyatt, Richard T; Barouch, Dan H; Crotty, Shane; Burton, Dennis R.

Immunity ; 46(6): 1073-1088.e6, 2017 06 20.

Artigo em Inglês | MEDLINE | ID: mdl-28636956

18.

A Bivalent Omicron-Containing Booster Vaccine against Covid-19.

Chalkias, Spyros; Harper, Charles; Vrbicky, Keith; Walsh, Stephen R; Essink, Brandon; Brosz, Adam; McGhee, Nichole; Tomassini, Joanne E; Chen, Xing; Chang, Ying; Sutherland, Andrea; Montefiori, David C; Girard, Bethany; Edwards, Darin K; Feng, Jing; Zhou, Honghong; Baden, Lindsey R; Miller, Jacqueline M; Das, Rituparna.

N Engl J Med ; 387(14): 1279-1291, 2022 10 06.

Artigo em Inglês | MEDLINE | ID: mdl-36112399

19.

Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age.

Creech, C Buddy; Anderson, Evan; Berthaud, Vladimir; Yildirim, Inci; Atz, Andrew M; Melendez Baez, Ivan; Finkelstein, Daniel; Pickrell, Paul; Kirstein, Judith; Yut, Clifford; Blair, Ronald; Clifford, Robert A; Dunn, Michael; Campbell, James D; Montefiori, David C; Tomassini, Joanne E; Zhao, Xiaoping; Deng, Weiping; Zhou, Honghong; Ramirez Schrempp, Daniela; Hautzinger, Kelly; Girard, Bethany; Slobod, Karen; McPhee, Roderick; Pajon, Rolando; Das, Rituparna; Miller, Jacqueline M; Schnyder Ghamloush, Sabine.

N Engl J Med ; 386(21): 2011-2023, 2022 05 26.

Artigo em Inglês | MEDLINE | ID: mdl-35544369

20.

Homologous and Heterologous Covid-19 Booster Vaccinations.

Atmar, Robert L; Lyke, Kirsten E; Deming, Meagan E; Jackson, Lisa A; Branche, Angela R; El Sahly, Hana M; Rostad, Christina A; Martin, Judith M; Johnston, Christine; Rupp, Richard E; Mulligan, Mark J; Brady, Rebecca C; Frenck, Robert W; Bäcker, Martín; Kottkamp, Angelica C; Babu, Tara M; Rajakumar, Kumaravel; Edupuganti, Srilatha; Dobrzynski, David; Coler, Rhea N; Posavad, Christine M; Archer, Janet I; Crandon, Sonja; Nayak, Seema U; Szydlo, Daniel; Zemanek, Jillian A; Dominguez Islas, Clara P; Brown, Elizabeth R; Suthar, Mehul S; McElrath, M Juliana; McDermott, Adrian B; O'Connell, Sarah E; Montefiori, David C; Eaton, Amanda; Neuzil, Kathleen M; Stephens, David S; Roberts, Paul C; Beigel, John H.

N Engl J Med ; 386(11): 1046-1057, 2022 03 17.

Artigo em Inglês | MEDLINE | ID: mdl-35081293

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