Detalhe da pesquisa
1.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
J Hepatol
; 80(2): 268-281, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37939855
2.
Acetaminophen overdose causes a breach of the blood-bile barrier in mice but not in rats.
Arch Toxicol
; 98(5): 1533-1542, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38466352
3.
Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen.
Exp Cell Res
; 381(2): 256-264, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31112736
4.
Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.
J Lipid Res
; 60(9): 1590-1602, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363040
5.
Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation.
J Lipid Res
; 60(6): 1078-1086, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962310
6.
Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia.
J Lipid Res
; 57(7): 1231-42, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27140664
7.
Tamoxifen regulation of sphingolipid metabolism--Therapeutic implications.
Biochim Biophys Acta
; 1851(9): 1134-45, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25964209
8.
Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Biochim Biophys Acta
; 1851(7): 919-28, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25769964
9.
Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells.
Biochim Biophys Acta
; 1831(12): 1657-64, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23939396
10.
A novel semisynthetic inhibitor of the FRB domain of mammalian target of rapamycin blocks proliferation and triggers apoptosis in chemoresistant prostate cancer cells.
Mol Pharmacol
; 83(2): 531-41, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23208958
11.
Arglabin, an EGFR receptor tyrosine kinase inhibitor, suppresses proliferation and induces apoptosis in prostate cancer cells.
Biomed Pharmacother
; 156: 113873, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36272260
12.
(8R)-3ß,8-dihydroxypolypoda-13E,17E,21-triene induces cell cycle arrest and apoptosis in treatment-resistant prostate cancer cells.
J Nat Prod
; 74(8): 1731-6, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21800858
13.
Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells.
Mol Pharmacol
; 77(3): 378-87, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20018812
14.
The Onus of Sphingolipid Enzymes in Cancer Drug Resistance.
Adv Cancer Res
; 140: 235-263, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30060811
15.
Oleanolic acid methyl ester, a novel cytotoxic mitocan, induces cell cycle arrest and ROS-Mediated cell death in castration-resistant prostate cancer PC-3 cells.
Biomed Pharmacother
; 96: 417-425, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29031200
16.
Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer.
Biochem Pharmacol
; 130: 21-33, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28189725
17.
Short-chain ceramides depress integrin cell surface expression and function in colorectal cancer cells.
Cancer Lett
; 376(2): 199-204, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27045476
18.
Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
Oncotarget
; 7(50): 83208-83222, 2016 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27825124
19.
Dynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemia.
Leuk Res
; 39(10): 1071-8, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26220867
20.
Ceramide-orchestrated signalling in cancer cells.
Nat Rev Cancer
; 13(1): 51-65, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23235911