Detalhe da pesquisa
1.
Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.
Blood
; 139(26): 3737-3751, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35443029
2.
Targeting human CALR-mutated MPN progenitors with a neoepitope-directed monoclonal antibody.
EMBO Rep
; 23(4): e52904, 2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35156745
3.
Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1.
Biochem J
; 476(21): 3211-3226, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31652307
4.
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
Blood
; 129(6): 771-782, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27956387
5.
The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism.
Sci Rep
; 12(1): 454, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013382
6.
Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1.
J Biol Chem
; 285(1): 483-92, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19854831
7.
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling.
J Exp Med
; 201(1): 49-54, 2005 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15623571
8.
Over-expression of sphingosine kinase-1 enhances a progenitor phenotype in human endothelial cells.
Microcirculation
; 18(7): 583-97, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21672077
9.
Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.
Oncogene
; 38(8): 1151-1165, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30250299
10.
Attenuation of leakiness in doxycycline-inducible expression via incorporation of 3' AU-rich mRNA destabilizing elements.
Biotechniques
; 45(2): 155-6, 158, 160 passim, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18687064
11.
CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1.
Cancer Res
; 77(18): 4823-4834, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729416
12.
Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress.
Oncotarget
; 8(27): 43602-43616, 2017 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467788
13.
An oncogenic role for sphingosine kinase 2.
Oncotarget
; 7(40): 64886-64899, 2016 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27588496
14.
A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties.
Oncotarget
; 6(9): 7065-83, 2015 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25788259
15.
A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1.
Int J Biochem Cell Biol
; 43(3): 342-7, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21075214
16.
The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1.
Int J Biochem Cell Biol
; 41(4): 822-7, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18775504
17.
Eukaryotic elongation factor 1A interacts with sphingosine kinase and directly enhances its catalytic activity.
J Biol Chem
; 283(15): 9606-14, 2008 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18263879
18.
Deactivation of sphingosine kinase 1 by protein phosphatase 2A.
J Biol Chem
; 283(50): 34994-5002, 2008 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18852266
19.
The calmodulin-binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane.
J Biol Chem
; 281(17): 11693-701, 2006 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16522638
20.
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling.
J Biol Chem
; 277(10): 7996-8003, 2002 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-11777919