Detalhe da pesquisa
1.
Role of non-coding RNAs on liver metabolism and NAFLD pathogenesis.
Hum Mol Genet
; 31(R1): R4-R21, 2022 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35417923
2.
Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice.
J Biol Chem
; 292(25): 10455-10464, 2017 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28483921
3.
Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver.
J Biol Chem
; 289(9): 5510-7, 2014 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24398675
4.
Enhancing hepatic mitochondrial fatty acid oxidation stimulates eating in food-deprived mice.
Am J Physiol Regul Integr Comp Physiol
; 308(2): R131-7, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25427767
5.
Insights from a high-fat diet fed mouse model with a humanized liver.
PLoS One
; 17(5): e0268260, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35533183
6.
Aberrant gene expression induced by a high fat diet is linked to H3K9 acetylation in the promoter-proximal region.
Biochim Biophys Acta Gene Regul Mech
; 1864(3): 194691, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33556624
7.
Gene therapy for inherited retinal and optic nerve degenerations.
Expert Opin Biol Ther
; 18(1): 37-49, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29057663
8.
Impact of silencing hepatic SREBP-1 on insulin signaling.
PLoS One
; 13(5): e0196704, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29723221
9.
Gene therapy for age-related macular degeneration.
Expert Opin Biol Ther
; 17(10): 1235-1244, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28726562
10.
Gene targets of mouse miR-709: regulation of distinct pools.
Sci Rep
; 6: 18958, 2016 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26743462
11.
Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats.
Diabetes
; 51(1): 130-8, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11756332
12.
Novel targets and therapeutic strategies for type 2 diabetes.
Trends Endocrinol Metab
; 14(4): 169-75, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12714277
13.
Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes.
Hum Gene Ther
; 13(13): 1561-70, 2002 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12228011
14.
Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons.
Hum Gene Ther
; 13(1): 143-54, 2002 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11779418
15.
Vector and helper genome rearrangements occur during production of helper-dependent adenoviral vectors.
Hum Gene Ther Methods
; 24(1): 1-10, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23249343
16.
shRNA-induced interferon-stimulated gene analysis.
Methods Mol Biol
; 820: 163-77, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22131031
17.
Comparative nucleic acid transfection efficacy in primary hepatocytes for gene silencing and functional studies.
BMC Res Notes
; 4: 8, 2011 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21244687
18.
Constitutive expression of short hairpin RNA in vivo triggers buildup of mature hairpin molecules.
Hum Gene Ther
; 22(12): 1483-97, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21780944
19.
Accurate single-day titration of adenovirus vectors based on equivalence of protein VII nuclear dots and infectious particles.
J Virol Methods
; 159(2): 251-8, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19406166
20.
Robust hepatic gene silencing for functional studies using helper-dependent adenoviral vectors.
Hum Gene Ther
; 20(1): 87-94, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18828727