Detalhe da pesquisa
1.
Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications.
Pharmacol Rev
; 73(2): 763-791, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33674359
2.
Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search.
Mol Psychiatry
; 27(10): 4144-4156, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35768639
3.
Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.
Nature
; 549(7673): 533-537, 2017 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28959975
4.
Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability.
Mol Psychiatry
; 26(11): 6704-6722, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33859356
5.
NMDAR inhibition-independent antidepressant actions of ketamine metabolites.
Nature
; 533(7604): 481-6, 2016 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27144355
6.
(2R,6R)-hydroxynorketamine exerts mGlu2 receptor-dependent antidepressant actions.
Proc Natl Acad Sci U S A
; 116(13): 6441-6450, 2019 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867285
7.
Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.
Proc Natl Acad Sci U S A
; 116(11): 5160-5169, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30796190
8.
Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.
Pharmacol Rev
; 70(3): 621-660, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945898
9.
Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures.
J Infect Dis
; 218(suppl_5): S672-S678, 2018 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29939303
10.
Time will tell. Reply to "Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al." by Chen et al.
Mol Psychiatry
; 27(4): 1863-1865, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35194167
11.
The show must go on. Reply to "Distinct functions of S-ketamine and R-ketamine in mediating biobehavioral processes of drug dependency: comments on Bonaventura et al" by Insop Shim.
Mol Psychiatry
; 2022 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35732692
12.
Zanos et al. reply.
Nature
; 546(7659): E4-E5, 2017 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28640272
13.
EVALUATION OF BLOOD GAS VALUES IN ANESTHETIZED SOUTHERN WHITE RHINOCEROS ( CERATOTHERIUM SIMUM) VENTILATED WITH A NOVEL DEMAND VENTILATOR IN A ZOOLOGICAL PARK SETTING.
J Zoo Wildl Med
; 48(4): 1016-1025, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29297798
14.
Comparative Assessment and High-Throughput Drug-Combination Profiling of TEAD-Palmitoylation Inhibitors in Hippo Pathway Deficient Mesothelioma.
Pharmaceuticals (Basel)
; 16(12)2023 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38139762
15.
Palladium-catalyzed diastereo- and enantioselective formal [3 + 2]-cycloadditions of substituted vinylcyclopropanes.
J Am Chem Soc
; 134(42): 17823-31, 2012 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23030714
16.
Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (2,6)- and (5R)-Methyl-(2R,6R)-hydroxynorketamines.
ACS Chem Neurosci
; 13(4): 510-523, 2022 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35113535
17.
Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration.
Transl Psychiatry
; 12(1): 179, 2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35501309
18.
18F-labeled radiotracers for in vivo imaging of DREADD with positron emission tomography.
Eur J Med Chem
; 213: 113047, 2021 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33280897
19.
A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801.
Neurotoxicol Teratol
; 87: 106993, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33945878
20.
Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo.
Microorganisms
; 9(3)2021 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33801811