Detalhe da pesquisa
1.
p53 amyloid pathology is correlated with higher cancer grade irrespective of the mutant or wild-type form.
J Cell Sci
; 136(17)2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37622400
2.
Protein misfolding and amyloid nucleation through liquid-liquid phase separation.
Chem Soc Rev
; 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38597222
3.
Modulating α-Synuclein Liquid-Liquid Phase Separation.
Biochemistry
; 60(48): 3676-3696, 2021 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34431665
4.
A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.
N Engl J Med
; 378(12): 1096-1106, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29562163
5.
Successes of genome-wide association studies.
Cell
; 142(3): 350-1; author reply 353-5, 2010 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20691890
6.
Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing.
JAMA
; 318(9): 825-835, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28873162
7.
Excess of homozygosity in the major histocompatibility complex in schizophrenia.
Hum Mol Genet
; 23(22): 6088-95, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24943592
8.
Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment.
Am J Med Genet B Neuropsychiatr Genet
; 168B(5): 363-73, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25951819
9.
Liquid-liquid Phase Separation of α-Synuclein: A New Mechanistic Insight for α-Synuclein Aggregation Associated with Parkinson's Disease Pathogenesis.
J Mol Biol
; 435(1): 167713, 2023 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35787838
10.
Amyloid fibril-based thixotropic hydrogels for modeling of tumor spheroids in vitro.
Biomaterials
; 295: 122032, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36791521
11.
Intermolecular interactions underlie protein/peptide phase separation irrespective of sequence and structure at crowded milieu.
Nat Commun
; 14(1): 6199, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794023
12.
NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects.
Clin Cancer Res
; 29(2): 422-431, 2023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346689
13.
Clonal Hematopoiesis and Risk of Incident Lung Cancer.
J Clin Oncol
; 41(7): 1423-1433, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36480766
14.
Including additional controls from public databases improves the power of a genome-wide association study.
Hum Hered
; 72(1): 21-34, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21849791
15.
Whole-genome sequencing of East Asian lung cancers reveals new germline pathogenic variants.
Cancer Cell
; 40(10): 1081-1083, 2022 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179687
16.
Phase separation and other forms of α-Synuclein self-assemblies.
Essays Biochem
; 66(7): 987-1000, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36373662
17.
Intermediates of α-synuclein aggregation: Implications in Parkinson's disease pathogenesis.
Biophys Chem
; 281: 106736, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923391
18.
A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos.
Sci Transl Med
; 14(665): eabo1050, 2022 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36197962
19.
Development and Validation of a Breast Cancer Polygenic Risk Score on the Basis of Genetic Ancestry Composition.
JCO Precis Oncol
; 6: e2200084, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36331239
20.
Multiple Primary Cancers in Patients Undergoing Tumor-Normal Sequencing Define Novel Associations.
Cancer Epidemiol Biomarkers Prev
; 31(2): 362-371, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34810208