Detalhe da pesquisa
1.
Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.
Cell
; 178(5): 1159-1175.e17, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31442405
2.
Prediction of disease-free survival for precision medicine using cooperative learning on multi-omic data.
Brief Bioinform
; 25(4)2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38836403
3.
A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets.
Brief Bioinform
; 24(1)2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36585781
4.
On the effect heterogeneity of established disease susceptibility loci for Alzheimer's disease across different genetic ancestries.
Alzheimers Dement
; 20(5): 3397-3405, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38563508
5.
Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2.
Mol Psychiatry
; 27(4): 1963-1969, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35246634
6.
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
Alzheimers Dement
; 17(9): 1509-1527, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33797837
7.
Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment.
Hum Mol Genet
; 26(8): 1472-1482, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28186563
8.
No association between CALHM1 and Alzheimer's disease risk.
Cell
; 135(6): 993-4; author reply 994-6, 2008 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19070563
9.
Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.
Alzheimers Dement
; 13(4): 381-387, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27520774
10.
PLD3 gene variants and Alzheimer's disease.
Nature
; 520(7545): E7-8, 2015 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25832413
11.
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.
Nat Genet
; 39(1): 17-23, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17192785
12.
Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families.
BMC Med Genet
; 16: 62, 2015 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26286599
13.
A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data.
Genes (Basel)
; 13(1)2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35052450
14.
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.
Hum Mol Genet
; 18(20): 3987-96, 2009 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19608551
15.
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.
Am J Hum Genet
; 83(5): 623-32, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18976728
16.
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
medRxiv
; 2020 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33173892
17.
Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.
Sci Rep
; 10(1): 5029, 2020 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32193444
18.
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
Nat Med
; 26(8): 1256-1263, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32572268
19.
Assessment of Alzheimer's disease case-control associations using family-based methods.
Neurogenetics
; 10(1): 19-25, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18830724
20.
Family-based association between Alzheimer's disease and variants in UBQLN1.
N Engl J Med
; 352(9): 884-94, 2005 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15745979