Detalhe da pesquisa
1.
Labeling Preferences of Diazirines with Protein Biomolecules.
J Am Chem Soc
; 143(17): 6691-6700, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33876925
2.
Structural and conformational determinants of macrocycle cell permeability.
Nat Chem Biol
; 12(12): 1065-1074, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27748751
3.
Erratum: Structural and conformational determinants of macrocycle cell permeability.
Nat Chem Biol
; 13(8): 922, 2017 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28853740
4.
Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.
J Org Chem
; 77(17): 7187-211, 2012 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853001
5.
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules.
Front Chem
; 10: 1002547, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36300022
6.
Catalytic diastereoselective petasis reactions.
Angew Chem Int Ed Engl
; 50(35): 8172-5, 2011 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21751322
7.
Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase.
J Med Chem
; 50(20): 4909-16, 2007 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-17824599
8.
Editorial: Coumarins: New synthetic approaches and new pharmacological applications.
Front Chem
; 10: 1124816, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36688054
9.
Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile.
ACS Infect Dis
; 3(5): 349-359, 2017 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215073
10.
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases.
J Med Chem
; 58(14): 5561-78, 2015 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26107513
11.
Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.
PLoS One
; 10(3): e0120295, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25811180
12.
Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties.
J Med Chem
; 57(6): 2746-54, 2014 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24524242
13.
Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents.
J Med Chem
; 57(20): 8496-502, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25211597
14.
Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease.
ACS Med Chem Lett
; 5(2): 149-53, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900788
15.
Short synthesis of skeletally and stereochemically diverse small molecules by coupling petasis condensation reactions to cyclization reactions.
Angew Chem Int Ed Engl
; 45(22): 3635-8, 2006 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-16646101
16.
Expanding stereochemical and skeletal diversity using petasis reactions and 1,3-dipolar cycloadditions.
Org Lett
; 12(22): 5230-3, 2010 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20977261
17.
Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B inhibitor.
J Med Chem
; 52(21): 6685-706, 2009 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19810674
18.
Screening of matrix metalloproteinases available from the protein data bank: insights into biological functions, domain organization, and zinc binding groups.
J Chem Inf Model
; 47(6): 2439-48, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17958346