Pesquisa | Biblioteca Virtual em Saúde

1.

Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells.

Yang, Wuchen; Guo, Dayong; Harris, Marie A; Cui, Yong; Gluhak-Heinrich, Jelica; Wu, Junjie; Chen, Xiao-Dong; Skinner, Charles; Nyman, Jeffry S; Edwards, James R; Mundy, Gregory R; Lichtler, Alex; Kream, Barbara E; Rowe, David W; Kalajzic, Ivo; David, Val; Quarles, Darryl L; Villareal, Demetri; Scott, Greg; Ray, Manas; Liu, S; Martin, James F; Mishina, Yuji; Harris, Stephen E.

J Cell Sci ; 126(Pt 18): 4085-98, 2013 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-23843612

2.

Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease.

Fowler, Jessica A; Lwin, Seint T; Drake, Matthew T; Edwards, James R; Kyle, Robert A; Mundy, Gregory R; Edwards, Claire M.

Blood ; 118(22): 5872-82, 2011 Nov 24.

Artigo em Inglês | MEDLINE | ID: mdl-21908434

3.

Bone metastasis: can osteoclasts be excluded?

Martin, T John; Mundy, Gregory R.

Nature ; 445(7130): E19; discussion E19-20, 2007 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-17314931

4.

Metastasis to bone: causes, consequences and therapeutic opportunities.

Mundy, Gregory R.

Nat Rev Cancer ; 2(8): 584-93, 2002 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-12154351

5.

The osteoclast-not always guilty.

Mundy, Gregory R; Edwards, James R.

Cell Metab ; 6(3): 157-9, 2007 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-17767902

6.

Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.

Ganapathy, Vidya; Ge, Rongrong; Grazioli, Alison; Xie, Wen; Banach-Petrosky, Whitney; Kang, Yibin; Lonning, Scott; McPherson, John; Yingling, Jonathan M; Biswas, Swati; Mundy, Gregory R; Reiss, Michael.

Mol Cancer ; 9: 122, 2010 May 26.

Artigo em Inglês | MEDLINE | ID: mdl-20504320

7.

Theoretical investigation of the role of the RANK-RANKL-OPG system in bone remodeling.

Pivonka, Peter; Zimak, Jan; Smith, David W; Gardiner, Bruce S; Dunstan, Colin R; Sims, Natalie A; Martin, T John; Mundy, Gregory R.

J Theor Biol ; 262(2): 306-16, 2010 Jan 21.

Artigo em Inglês | MEDLINE | ID: mdl-19782692

8.

Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation.

Zhao, Ming; Harris, Stephen E; Horn, Diane; Geng, Zhaopo; Nishimura, Riko; Mundy, Gregory R; Chen, Di.

J Cell Biol ; 157(6): 1049-60, 2002 Jun 10.

Artigo em Inglês | MEDLINE | ID: mdl-12058020

9.

Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.

Edwards, Claire M; Lwin, Seint T; Fowler, Jessica A; Oyajobi, Babatunde O; Zhuang, Junling; Bates, Andreia L; Mundy, Gregory R.

Am J Hematol ; 84(5): 268-72, 2009 May.

Artigo em Inglês | MEDLINE | ID: mdl-19296472

10.

The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling.

Zhao, Ming; Qiao, Mei; Harris, Stephen E; Chen, Di; Oyajobi, Babatunde O; Mundy, Gregory R.

Mol Cell Biol ; 26(16): 6197-208, 2006 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-16880529

11.

PTH-related peptide (PTHrP) in hypercalcemia.

Mundy, Gregory R; Edwards, James R.

J Am Soc Nephrol ; 19(4): 672-5, 2008 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-18256357

12.

The pathogenesis of the bone disease of multiple myeloma.

Edwards, Claire M; Zhuang, Junling; Mundy, Gregory R.

Bone ; 42(6): 1007-13, 2008 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-18406675

13.

Model structure and control of bone remodeling: a theoretical study.

Pivonka, Peter; Zimak, Jan; Smith, David W; Gardiner, Bruce S; Dunstan, Colin R; Sims, Natalie A; John Martin, T; Mundy, Gregory R.

Bone ; 43(2): 249-263, 2008 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-18514606

14.

Eph receptors and ephrin signaling pathways: a role in bone homeostasis.

Edwards, Claire M; Mundy, Gregory R.

Int J Med Sci ; 5(5): 263-72, 2008 Sep 03.

Artigo em Inglês | MEDLINE | ID: mdl-18797510

15.

Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor.

Bandyopadhyay, Abhik; Agyin, Joseph K; Wang, Long; Tang, Yuping; Lei, Xiufen; Story, Beryl M; Cornell, John E; Pollock, Bradley H; Mundy, Gregory R; Sun, Lu-Zhe.

Cancer Res ; 66(13): 6714-21, 2006 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-16818646

16.

The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells.

Sterling, Julie A; Oyajobi, Babatunde O; Grubbs, Barry; Padalecki, Susan S; Munoz, Steve A; Gupta, Anjana; Story, Beryl; Zhao, Ming; Mundy, Gregory R.

Cancer Res ; 66(15): 7548-53, 2006 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-16885353

17.

Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging.

Oyajobi, Babatunde O; Muñoz, Steve; Kakonen, Rami; Williams, Paul J; Gupta, Anjana; Wideman, Christi L; Story, Beryl; Grubbs, Barry; Armstrong, Allison; Dougall, William C; Garrett, I Ross; Mundy, Gregory R.

Mol Cancer Ther ; 6(6): 1701-8, 2007 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-17541032

18.

The polyphenol resveratrol promotes skeletal growth in mice through a sirtuin 1-bone morphogenic protein 2 longevity axis.

Zhao, Ming; Ko, Seon-Yle; Garrett, I Ross; Mundy, Gregory R; Gutierrez, Gloria E; Edwards, James R.

Br J Pharmacol ; 175(21): 4183-4192, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30125963

19.

Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo.

Gallwitz, Wolfgang E; Guise, Theresa A; Mundy, Gregory R.

J Clin Invest ; 110(10): 1559-72, 2002 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-12438453

20.

Caspase-2 deficiency enhances aging-related traits in mice.

Zhang, Yingpei; Padalecki, Susan S; Chaudhuri, Asish R; De Waal, Eric; Goins, Beth A; Grubbs, Barry; Ikeno, Yuji; Richardson, Arlan; Mundy, Gregory R; Herman, Brian.

Mech Ageing Dev ; 128(2): 213-21, 2007 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-17188333

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