Detalhe da pesquisa
1.
Respiratory complex I in mitochondrial membrane catalyzes oversized ubiquinones.
J Biol Chem
; 299(8): 105001, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37394006
2.
Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I.
J Biol Chem
; 298(3): 101602, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35063503
3.
Diverse reaction behaviors of artificial ubiquinones in mitochondrial respiratory complex I.
J Biol Chem
; 298(7): 102075, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35643318
4.
Pinpoint Dual Chemical Cross-Linking Explores the Structural Dynamics of the Ubiquinone Reaction Site in Mitochondrial Complex I.
Biochemistry
; 60(10): 813-824, 2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33650850
5.
IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells, inhibits mitochondrial respiratory complex I through a unique mechanism.
J Biol Chem
; 295(21): 7481-7491, 2020 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32295842
6.
Inhibitors of a Na+-pumping NADH-ubiquinone oxidoreductase play multiple roles to block enzyme function.
J Biol Chem
; 295(36): 12739-12754, 2020 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690607
7.
Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I.
J Biol Chem
; 295(8): 2449-2463, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31953326
8.
Natural tetramic acids elicit multiple inhibitory actions against mitochondrial machineries presiding over oxidative phosphorylation.
Biosci Biotechnol Biochem
; 85(12): 2368-2377, 2021 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34625801
9.
Traminines A and B, produced by Fusarium concentricum, inhibit oxidative phosphorylation in Saccharomyces cerevisiae mitochondria.
J Ind Microbiol Biotechnol
; 48(9-10)2021 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34343309
10.
Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I by chemical biology approaches.
J Biol Chem
; 294(2): 679-696, 2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425100
11.
Defining the mechanism of action of S1QELs, specific suppressors of superoxide production in the quinone-reaction site in mitochondrial complex I.
J Biol Chem
; 294(16): 6550-6561, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30824536
12.
Exploring the binding pocket of quinone/inhibitors in mitochondrial respiratory complex I by chemical biology approaches.
Biosci Biotechnol Biochem
; 84(7): 1322-1331, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32264779
13.
Antibiotic Korormicin A Kills Bacteria by Producing Reactive Oxygen Species.
J Bacteriol
; 201(11)2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858300
14.
Pentenediol-Type Compounds Specifically Bind to Voltage-Dependent Anion Channel 1 in Saccharomyces cerevisiae Mitochondria.
Biochemistry
; 58(8): 1141-1154, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30657320
15.
Epoxycyclohexenedione-Type Compounds Make Up a New Class of Inhibitors of the Bovine Mitochondrial ADP/ATP Carrier.
Biochemistry
; 57(6): 1031-1044, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29313673
16.
Identification of the binding sites for ubiquinone and inhibitors in the Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae by photoaffinity labeling.
J Biol Chem
; 292(19): 7727-7742, 2017 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28298441
17.
Synthetic Ubiquinones Specifically Bind to Mitochondrial Voltage-Dependent Anion Channel 1 (VDAC1) in Saccharomyces cerevisiae Mitochondria.
Biochemistry
; 56(4): 570-581, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28051849
18.
Pinpoint Chemical Modification of the Quinone-Access Channel of Mitochondrial Complex I via a Two-Step Conjugation Reaction.
Biochemistry
; 56(32): 4279-4287, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28707880
19.
Current topics on inhibitors of respiratory complex I.
Biochim Biophys Acta
; 1857(7): 884-91, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26625959
20.
Reduction of Synthetic Ubiquinone QT Catalyzed by Bovine Mitochondrial Complex I Is Decoupled from Proton Translocation.
Biochemistry
; 55(3): 470-81, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26701224