Detalhe da pesquisa
1.
Human PLD structures enable drug design and characterization of isoenzyme selectivity.
Nat Chem Biol
; 16(4): 391-399, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32042197
2.
Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors.
Bioorg Med Chem Lett
; 60: 128549, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35041943
3.
Bioseparation of phycocyanin from Phormidium tergestinum using an aqueous two-phase system.
Prep Biochem Biotechnol
; 51(3): 260-266, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32876520
4.
Influence of freeze-drying and spray-drying preservation methods on survivability rate of different types of protectants encapsulated Lactobacillus acidophilus FTDC 3081.
Biosci Biotechnol Biochem
; 84(9): 1913-1920, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32448058
5.
Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity.
Bioorg Med Chem Lett
; 28(10): 1964-1971, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29636220
6.
Corrigendum to "Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors" [Bioorg. Med. Chem. Lett. 60 (2022) 128549].
Bioorg Med Chem Lett
; 72: 128856, 2022 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35728998
7.
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis.
J Med Chem
; 67(10): 8122-8140, 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712838
8.
Elucidation of the GSK3α Structure Informs the Design of Novel, Paralog-Selective Inhibitors.
ACS Chem Neurosci
; 14(6): 1080-1094, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36812145
9.
Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase.
iScience
; 25(1): 103650, 2022 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35024585
10.
Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis.
J Med Chem
; 65(2): 1206-1224, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34734694
11.
Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo.
J Med Chem
; 64(20): 15402-15419, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34653340
12.
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo.
J Med Chem
; 64(9): 6358-6380, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33944571
13.
Investigation of potential anti-urolithiatic activity from different types of Musa pseudo-stem extracts in inhibition of calcium oxalate crystallization.
BMC Complement Med Ther
; 20(1): 317, 2020 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33076892
14.
Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors.
ACS Med Chem Lett
; 11(4): 485-490, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292554
15.
Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors.
J Med Chem
; 62(23): 10740-10756, 2019 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31710475
16.
Green Nanotechnology for Synthesis and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) nanoparticles for sustained bortezomib release using supercritical CO2 assisted particle formation combined with electrodeposition.
Int J Biol Macromol
; 107(Pt A): 436-445, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28888547
17.
CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling.
Sci Signal
; 11(541)2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30065029
18.
Biosynthesis of P(3HB-co-3HHx) with improved molecular weights from a mixture of palm olein and fructose by Cupriavidus necator Re2058/pCB113.
Int J Biol Macromol
; 102: 1112-1119, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28476592
19.
Validation of thermally assisted hydrolysis and methylation-gas chromatography for rapid and direct compositional analysis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) in whole bacterial cells.
J Chromatogr A
; 1471: 186-191, 2016 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27769532
20.
A new biological recovery approach for PHA using mealworm, Tenebrio molitor.
J Biotechnol
; 239: 98-105, 2016 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27746304