Detalhe da pesquisa
1.
Comparative Analysis of Cyclization Techniques in Stapled Peptides: Structural Insights into Protein-Protein Interactions in a SARS-CoV-2 Spike RBD/hACE2 Model System.
Int J Mol Sci
; 25(1)2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38203338
2.
Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats.
Am J Physiol Heart Circ Physiol
; 320(4): H1646-H1656, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33635165
3.
Simultaneous Ligand and Receptor Tracking through NMR Spectroscopy Enabled by Distinct 19F Labels.
Int J Mol Sci
; 20(15)2019 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31357423
4.
The hypotensive effect of activated apelin receptor is correlated with ß-arrestin recruitment.
Pharmacol Res
; 131: 7-16, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29530600
5.
ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock.
Crit Care Med
; 45(11): e1139-e1148, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28777197
6.
Structure-activity relationship of novel macrocyclic biased apelin receptor agonists.
Org Biomol Chem
; 15(2): 449-458, 2017 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27924341
7.
Intracuff 160 mg alkalinized lidocaine reduces cough upon emergence from N2O-free general anesthesia: a randomized controlled trial.
Can J Anaesth
; 63(7): 862-70, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27075030
8.
Stability and degradation patterns of chemically modified analogs of apelin-13 in plasma and cerebrospinal fluid.
Biopolymers
; 102(4): 297-303, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24728860
9.
Localized apelin-17 analogue-bicelle interactions as a facilitator of membrane-catalyzed receptor recognition and binding.
Biochim Biophys Acta Biomembr
; 1866(3): 184289, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38278504
10.
Optimization of Ketobenzothiazole-Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication.
ChemMedChem
; 19(2): e202300458, 2024 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37864572
11.
From garden to lab: C-3 chemical modifications of tomatidine unveil broad-spectrum ATP synthase inhibitors to combat bacterial resistance.
Eur J Med Chem
; 262: 115886, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37924710
12.
Signaling Modulation via Minimal C-Terminal Modifications of Apelin-13.
ACS Pharmacol Transl Sci
; 6(2): 290-305, 2023 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798478
13.
Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects.
J Med Chem
; 65(1): 531-551, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34982553
14.
Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor.
J Med Chem
; 64(1): 602-615, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33350824
15.
Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile.
J Med Chem
; 64(9): 5345-5364, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33524256
16.
Inhibitors of type II transmembrane serine proteases in the treatment of diseases of the respiratory tract - A review of patent literature.
Expert Opin Ther Pat
; 30(11): 807-824, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32887532
17.
Data set describing the in vitro biological activity of JMV2009, a novel silylated neurotensin(8-13) analog.
Data Brief
; 31: 105884, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32637491
18.
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog.
Eur J Pharmacol
; 882: 173174, 2020 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32534076
19.
A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects.
J Med Chem
; 61(6): 2266-2277, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29461833
20.
The signaling signature of the neurotensin type 1 receptor with endogenous ligands.
Eur J Pharmacol
; 805: 1-13, 2017 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28341345